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Layers of the head to brain
Scalp
Epicranial Aponeurosis
Cranium (bone layer)
Dura Mater
Arachnoid mater
Pis mater (covering cerebral cortex)

6 major regions of the brain
Cerebrum
Cerebellum
Medulla oblongata
Pons
Mesencephalon (midbrain)
Diencephalon

Cerebral Hemispheres (cerebrum)
left:
- receives and send motor output to the right side of the body
right:
- receives info and sends motor output to the left side of the body
What separates both hemispheres
Longitudinal fissure
what connects both hemispheres
Corupus callosum
Cortex (gray matter)
sulci - the groves
gyri- folds/ridges
both make up the surface of the cortex

Basal Ganglia
produces dopamine
subcortical - under cerebral cortex
Limbic System
nuclei & cortical structures:
- thalamus
- hypothalamus
- hippocampus
- amygdala (memory, decision making)
- olfactory bulb (sense of smell, emotion & memory)
what are the 4 lobes of the cerebrum?
frontal, parietal, temporal, occipital
frontal lobe
- contains prefrontal cortex
- primary motor cortex
- center for motor control
parietal lobe
- primary somatosensory cortex
- somatosensory association area
- takes in sense info & process it in the association area
temporal lobe
- auditory cortex
- olfactory cortex
occipital lobe
- center for vision
- visual association area
cerebellum
- controls balance & smooth motor functions
- "little brain" in latin
medulla oblongata
relays sensory info to thalamus and other portions of the brainstem
pons
- relays sensory info to cerebellum and thalamus
- "bridge" in latin
- point of cranial nerves
mesecephalon (midbrain)
- processing of visual and auditory data
- generating reflexive somatic motor response
- maintaining consciousness
- "middle" in Greek
Diencephalon (subdivisions)
- subcortical area
Subdivisions:
- epithalamus (3rd eye)
- thalamus
- hypothalamus
epithalamus
- 3rd eye
- pineal gland (endocrine gland) produce melatonin to support sleep cycles
- posterior to thalamus and hypothalamus

thalamus
relays and processes sensory information

hypothalamus
- inferior to thalamus
- important to nerve and endocrine systems
- role in controlling emotions

Ventricles of the brain (4)
- cerebral spinal fluid is made here
-lateral ventricles (1&2, in the 2 hemispheres)
-3rd ventricle
-4th ventricle

interventricular foramen
allows communication from lateral ventricles to 3rd ventricle

cerebal aqueduct
allows communication fronm 3rd ventricle to 4th ventricle

cranial nerves (12 pairs, CNI - CnXII)
Olfactory
Optic
Oculomotor
Trochlea
Trigeminal
Abducens
Facial
Vestibulocochlear
Glossopharyngeal
Vagus
Accessory
Hypoglossal
nemonic: oh oh oh to touch ad feel very good velvet ah heaven
sensory, motor, both nemonic for cranial nerves
some say marry money but my brother says big brains matter more
4 nerve plexuses
cervical, brachial, lumbar, sacral
cervical plexus
C1-C4
- provide sensory input from head, neck, shoulder
- nerve root
- 2 cranial nerve 11 & 12
- 11 (accessory)
- 12 (hypoglossal nerve)
brachial plexus
C5-T1 (most complicated)
- spinal cord > 6 roots > 3 trunks > 2 division > 3 cords > nerves (read the damn cadaver notes)
- nerves come off of cords with specific names and functions
roots (C5-T1)
trunks (superior, middle, inferior)
division (anterior & posterior)
cords (posterior, lateral, medial)

trunks of brachial plexus
superior C5-C6
middle C7
inferior C8&T1
Lateral cord of brachial plexus
superior division of (superior and middle trunk)
Medial cord of brachial plexus
anterior division of inferior trunk
posterior cord of brachial plexus
takes all trunks
lumbar plexus
T12-L4
- provide innervation to some abdominal muscles
- innervate to thigh
- sensory to regions of the thigh, genitalia, leg, foot
sacral plexus
L4-S4
- provide muscular innervation to glutes, leg muscles
- sensory to posterior thigh & leg
- motor of sphincter muscles
- sensory to genitalia
sciatic nerve (sacral plexus)
- biggest nerve in human body
- runs down posterior leg
- splits into tibial and common fibular nerve
Dermatomes (sacral plexus)
area of the skin that is mainly supplied by branches of a single spinal sensory nerve root
Reflex
- immediate involuntary motor response
Reflex arc
- neural "wiring" of a single reflex
- begins at a sensory receptor and ends at a peripheral effector
Contralateral
on the opposite side of the body from another structure
CNI
Olfactory (Sensory):
- smell
- olfactory nerves fibers from from cribriform plate of ethmoid

CNII
Optic (sensory):
- vision
- visual info to ganglia

CNIII
Oculomotor (motor):
- eye muscles
- 6 extra ocular muscles that move the eye ball around
- 4/6 controlled by ocular motor nerves
- innervates the levator palpebral (muscles that controls the eyelid)
- superior/inferior & medial rectus muscles & inferior oblique muscles innervated by oculi motor nerves
- inferior oblique contracts makes pupils go outward an dup
CNIV
Trochlea (motor):
- innervate superior oblique muscle
- when contracted draws pupils inferiorly & outward, opposite of inferior oblique
CNV
Trigeminal (sensory & motor):
- pick up sensory info from head and face
- provide motor muscles and mastication
CNVI
Abducens (motor):
- innervate lateral rectus muscles
CNVII
Facial (sensory):
- innervate muscles of facial expression
- provide sensation for part of ear and part of face
CNVIII
Vestibulocochlear (sensory):
CNIX
Glossopharyngeal (sensory & motor):
- vestibular division (balance)
- choclear division (hearing sensation)
- vertigo (damage to nerves, loss sense of balanceO
CNX
Vagus (sensory & motor):
- comes from brain stem and extends into visceral systems
- picks up sensory info from visceral systems and some external ear
CNXI
Accessory (motor):
- innervate accessory muscles (inspiration)
- used when trying to breath when you have difficulty
- receives fibers from cervical plexus
- sternocleidomastoid (inspiration muscles)
- trapezius (inspiration muscles)
CNXII
Hypoglossal (motor):
- sensory for tongue and pharynx
- motor to pharynx
The autonomic nervous system (ANS) functions.......?
outside of our conscious awareness
the ANS works hard to maintain....?
homestasis
the ANS controls?
body temp and internal systems (respiratory, digestive, reproductive, cardiovascular, excretory)
Neurons of autonomic nervous system
efferent axons: innervate visceral organs
afferent axons: originate in visceral sensory
receptors
Neurons in somatic nervous system
efferent axons: innervate skeletal muscles
afferent axons: originate in the skeletal
muscles, joints, and skin
subdivisions of ANS
sympathetic and parasympathetic
sympathetic divison
- also known as thoracolumbar division
- fight or flight system
- most active during time of stress, excitement, emergency
preganglionic neuron (sympathetic)
- located in lateral horns of spinal segments (T1-L2)
- release acetylcholine (ACh) which stimulates ganglionic neurons
ganglionic neurons
located in:
sympathetic chain ganglia
collateral ganglia
adrenal medulla
postganglionic fibers (sympathetic)
- release norepinephrine
organs during sympathetic (fight or flight)
-heart/respiratory rate increases
- digestive system, urination system & reproductive system inhibited
- pupils dilate
Adrenal medulla
-releases epinephrine (adrenaline) and norepinephrine (noradrenaline)
- circulating blood distributes these hormones throughout the body
parasympathetic division
- also known as craniosacral division (rest & digest)
- more active during resting conditions
preganglionic neuron of parasympathetic division
-located in brainstem and lateral portion of anterior horns of spinal segments (S2-S4)
-release ACh, excite & stimulates ganglionic neurons
- form distinct pelvic nerves
ganglionic neurons of parasympathetic
located in peripheral ganglia within or adjacent to the target organs
Enteric Nervous System (ENS)
- 3rd division of autonomic nervous system
- neurons located in walls of digestive tracts
- many visceral reflexes are initiated by ENS, but receive input from ANS
effects of sympathetic stimulation
-increase alertness (pupil dilation)
- feeling of energy & euphoria (excitement, high adrenaline)
- increased cardiovascular activity (faster Hr, more blood to muscles)
- increased respiratory activity (more O2 in)
- elevation in muscle tone
- mobilization of energy reserves ( fuel muscles, getting body ready for action)
effects of parasympathetic stimulation
- constrict pupils
- secretion of digestive glands
- secretion of hormones promoting nutrient absorption
- increased smooth muscle activity along digestive tract
- stimulate and coordination of defecation
- contracting urinary bladder during urination
- reduction of Hr
- constrict respiratory passageway
- sexual arousal
relationship between sympathetic and parasympathetic divisions
-duals innervation: most vital organs are innervated by both divisions
-both divisions often have opposite/ antagonistic effects
-part of maintaining homeostasis
release of ACh
sympathetic - preganglionic release ACh, postganglionic release noreepinephrine
parasympathetic - both pre- & postganglionic release ACh
Upper respiratory system
noce, nasal cavity, paranasal sinuses, and pahrynx
lower respirtory system
larynx, trachea, bronchi, lungs, bronchioles, alveoli
Functions of the Repiratory System
- gas exchange between air & blood
- moves air to and from exchange surface of lungs
- protects respiratory system from dehydration
- protection against invading pathogens
- produces sound in verbal communication
Respiratory Epithelium
contains numerous mucous cells that produce sticky mucus that bathes the exposed surfaces
contamination of inspired air by pathogens/debris will?
damage the delicate surfaces of respiratory system
what happens in the conducting portion of respiratory system?
filtration, warming and humidification of inhaled air
alveolar ducts and sacs / alveoli
alveolar duct: attachment point for respiratory bronchioles
alveolar sacs: end of alveolar ducts
alveoli: 150 million in each lung
capillaries surrounding alveolus
extensive network of capillaries drop off carbon dioxide and pick up oxygen
type 1 alveolar cells
lines alveoli
type 2 alveolar cells
- scattered among type 1 alveolar cells
- secrete surfactant that prevents alveolar collapse
alveolar macrophages
wander around phagocytizing (ingest) particulate matter
Gas exchange occurs where?
blood air barrier:
- alveolar cell layer
- capillary endothelium
- fused basement membrane between alveolar cells and capillary endothelium
gas exchange process
- CO2 leaves capillaries and enters the alveolar sacs
- O2 leaves alveolar sacs and enter the capillaries
blood supply to lungs
- pulmonary arteries branch repeatedly within lungs before supplying the pulmonary capillaries
- pulmonary veins deliver blood to heart
lung cancer
- aggressive class of malignancies
- affects epithelial cells lining conducting passageways or alveoli
right and left pleural cavities are separated by the... ?
mediastinum
serous membrane
- lines each lung
- made of 2 continuous layers (pleura)
visceral pleura: covers outer surface of lung
parietal pleura: covers inner lining of thoracic wall, mediastinum and superior surface of diaphragm
plerual cavity
fluid-filled space between visceral and parietal pleurae
pleural fluid
- reduced friction when lungs move upon inhalation and exhalation
pleurisy
may cause membranes to produce and secrete excess pleural fluid or cause inflamed pleurae to adhere to one another
ANS in pulmonary ventilation
adjust breathing rate and depth to body's metabolic needs
intricate neural circuits (ventilation)
relays info from brain, lungs and other sensors throughout the body to coordinate ventilatory control
what governs the normal respiratory cycle?
inherent activity of inspiratory neurons w/ cell bodies in medulla oblongata
what is known as the respiratory center?
medulla oblongata
neurons of medulla oblongata
activate diaphragm and intercostal muscles to cause lungs to inflate
What % of body weight is blood?
7%
pregnant women has ____% more blood
50%
blood helps to stabilize?
body temp