Prostaglandin Indications

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8 Terms

1
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Carboprost

Postpartum bleeding


2nd trimester abortions


ADR: bronchoconstriction, n/v/d, inc body temp


Can give IM b/c 15-methyl blocks oxidation

2
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Misoprostol

NSAID-induced gastric ulcer prevention in high-risk patients


ADR: abortion


Prodrug; food/antacids dec absorption

3
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Treprostinil

pulmonary arterial hypertension


ADR: hypotension, infusion site pain

Can give SC

4
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Iloprost

Pulmonary arterial hypertension


ADR: hypotension


Used via inhalation

5
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Prostin VR

ductus arteriosus dependent congenital heart defects

6
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Caverject, Edex, Muse

Erectile dysfunction

7
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Dinoprostone

Cervical ripening/labor induction


2nd trimester abortion, evacuation of uterus in fetal death

8
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Epoprostenol

Scleroderma, primary pulmonary hypertension