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What are the 4 major regions of the adult brain
Cerebrum
Diencephalon
Brain stem
Cerebellum
What is the cerebrum
Responsible for conscious thought, memory, sensation, language and voluntary movement
Contains the lobes
What is the diencephalon
Includes thalamus, hypothalamus and epithalamus
Involved in sensory relay and homeostasis
What is the brain stem
Consists of the midbrain, pons and medulla oblongata
Control vital functions and connects the brain to the spinal cord
What is the cerebellum
Coordinates movement, balance, posture and motor learning
What are the ventricles of the brain
Ventricles are the empty spaces within the brain and contain CSF
There are lateral ventricles (1st and 2nd) and then third and fourth
What is the lateral ventricles
Located within the left and right cerebral hemisphere
One ventricle in each hemisphere, largest ventricle
What is the 3rd ventricle
Located in diencephalon, between 2 halves of thalamus
Connected to the lateral ventricles by inter ventricular foramina
What is the 4th ventricle
Located between brainstem and cerebellum
Connected the 3rd ventricle by cerebral
Continues into central canal of the spinal cords
What are the functional areas of the cerebral cortex
Gyri
Sulcus
What is the gyri
Raised elevations
What is the sulcus
Shallow grooves
What are the major lobes of the cerebral cortex
Frontal
Parietal
Temporal
Occipital
Insula
What is the frontal lobe
Voluntary movement, planning, personality, speech production
What is the parietal lobe
Sensory perception (touch, pressure, pain, temperature and skin sensation)
What is the temporal lobe
Hearing, memory, smell and language comprehension
What is the occipital lobe
Responsible for vision
What is the Insula lobe
Responsible for taste, visceral sensation, emotions and balance
What are the fissures of the cerebral cortex
Longitudinal fissure
Central sulcus
Lateral cercus
Parieto occipital sulcus
What is the longitudinal fissure
Separates left and right cerebral hemisphere
What is the central sulcus
Separates frontal and parietal lobes
What is the lateral sulcus
Separates temporal lobe from frontal and parietal lobe
What is the Parieto occipital sulcus
Separates parietal and occipital lobes
What is the lateralisation of cortical function
The tendency for certain functions to be specialised in one cerebral hemisphere more than the other
They communicate through the corpus callosum
What is the left hemisphere responsible for
Language, speech, reading, writing, mathematics, logical thinking
What is the right hemisphere responsible for
Spatial awareness, creativity, imagination, facial recognition, music and emotional interpretation
What is the location of the diencephalon
Found deep within the brain, between cerebrum and brain stem, surrounding the 3rd ventricle
What are the subdivisions of the diencephalon
Thalamus
Hypothalamus
Epithalamus
What is the thalamus
Primary relay station for sensory inputs to the cerebral cortex
What is the hypothalamus
Maintains homeostasis by regulating temperature, hunger, thirst and emotions
What is the epithalamus
Contains pineal gland, secretes melatonin and help regulate sleep and wake rhythms
What is the brain stem
Connects the cerebrum to the spinal cord
What are the 3 major regions of the brain stem
Midbrain
Pons
Medulla oblongata
What is the midbrain
Contains visual and auditory reflex centres
Controls eye movements and motor control pathways
What is the pons
Relays information between the cerebrum and cerebellum and helps regulate breathing
What is the medulla oblongata
Controls vital autonomic centres that control HR, BP, breathing, swallowing, coughing and vomiting
What is the structure of the cerebellum
Located at the back of the brain, inferior to occipital lobes and posterior to the brain
Consists of two hemispheres connected by vermis and has highly folded outer cortex
What is the function of the cerebellum
Maintains balance and equilibrium
Coordinated voluntary movements
Regulates posture and muscle tone
Ensures movement are smooth, precise and coordinated
Involved in motor learning and memory
what are the meninges
3 connective tissue membranes that surround the brain and spinal cord
What are the 3 connective tissue membranes (meninges)
Dura matter: outer layer
Arachnoid matter: middle layer
Pia material: inner layer
What is the CSF
Cerebral spinal fluid
Clear fluid found in ventricles, central canal and subarachnoid space
What is the function of of the CSF
Cushions the brain and spinal cord from injury
Acts as a shock absorber
Provided buoyancy, reducing weight of the brain
Transports nutrient and removes waste products
What is the blood brain barrier
Formed by astrocytes and capillary tight junctions
What are the functions of the blood brain barrier
Prevents toxins and pathogens from entering the brain
Maintains stable chemical environment for neurons
Allows essential substance (oxygen and glucose) to enter
How is CSF formed
Produced by choroid plexus in the ventricles
The choroid plexus filters blood plasma to form CSF
What is the circulatory pathway of CSF
What is the gross structure of the spinal cord
2 cm wide
Grey matter on inside and white matter on outside
Contains the conus medullaris and the cauda equina
What is the conus medullaris
Where the spinal cord terminates before the end of the veterbral column
What is the cauda equina
Drooping of the lumbar and sacral nerve roots below conus medullaris
What is the filum terminale
An extension of the Pia mater
Anchors spinal cord to the coccyx
What is the microscopic structure of the spinal cord
Central canal
Posterior median sulcus
Anterior median fissures
Posterior (dorsal) horns
Anterior (ventral) horns
What is the central canal
Lined by ependymal cells and contains CSF
What is the peripheral nervous system
Consists of all nervous tissues outside hte brain and spinal cord
Contents CNS to the rest of the body, carries sensory information to and away from the CNS
What are the components of the peripheral nervous systems
Cranial nerves
Spinal nerve
Ganglia
Sensory receptors
What are the sensory receptors
Mechanoreceptors
Thermoreceptors
Photoreceptors
Chemoreceptors
Nocirecptors
What are Mechanoreceptors
Detect touch, pressure, vibration, stretch and hearing
Found in skin, muscles, tendons, joins and inner ear
What are Thermoreceptors
Respond to temperature change
Found in the skin and hypothalamus
What are photoreceptors
Respond to changes in light
Found in the retina of the eye
What are chemoreceptors
Respond to chemical in solution
Found in tastebuds, blood vessels and brain
What are nocireceptors
Respond to damaging stimuli and pain
Found everywhere
What is sensory perception
Conscious awareness and interpretation of sensory information by the cerebral cortex
Allows us to recognise and understand stimuli such as touch, temperature, pain, sound and light
What is sensory adaptation
A decrease in receptor sensibility and awareness of a constant, unchanging stimulus over time
As a result, the frequency of nerve impulses decrease
What is the structure of a nerve
Endoneurium (in) - surrounds individual axons
Perineurium (mid) - surrounds a bundle of axons
Epineurium (out) - surrounds entire nerve and binds fascicles together
What are the 12 cranial nerves
Olfactory - smell
Optic - vision
Oculomotor - 4 out of 6 eye muscles
Trochlear - pulley muscle of eye
Trigeminal - sensory fibres to face and jaw
Abducens - turns eyeball laterally
Facial - facial expression muscle
Vestibulocochlear - hearing and balance
Glossopharyngeal - swallowing
Vagus - parasympathetic control
Accessory - moves head and neck
Hypoglossol - tongue muscles and movement
What are the major plexuses
Central (C1-C4)
Brachial (C5-T1)
Lumbar (T12-L4)
Sacral (L4-S4)
Central plexus
Head, neck, shoulders and diaphragm
Phrenic nerve: controls diaphragm for breathing
Brachial plexus
Chest shoulders and arms
Axillary nerve (shoulder)
Radial nerve (posterior arm and forearm muscle)
Median (forearm and hand)
Ulnar (hand and medial forearm)
Lumbar plexus
Back, abdomen, growing and legs
Femoral nerve thigh flexion and knee extension
Sacral plexus
Pelvis, buttocks, genitals and legs
Sciatic nerve
What are the components of a reflex arc
Receptor - detects stimulus
Sensory neuron - carries signal
Integration centre - processes information in the CNS
Motor neuron - efferent pathway away from CNS
Effector - muscle or gland response, produces response
Difference between somatic and autonomic response
Autonomic - effector is the smooth or cardiac muscles internal organ function e.g. pupillary reflex
Somatic - effector is skeletal muscles controls body movement e.g. knee jerk reflex
What is the difference between stretch and withdrawal reflexes
Stretch - triggered when a muscle is stretched requires no interneuron. No brain input
Withdrawal reflex - triggered by a painful stimulus, protective reflex limb withdrawn. Requires interneuron. Involves brain input
what is a cholinergic receptors
responds and binds to acetylcholine
What are adrenergic receptors
Binds adrenaline and noradrenaline
Includes alpha and beta receptors