protein synthesis

Prototype of macrolide ?

Erythromycin

Which one used for treat H.pylori therapy?

Clarithromycin

Erythromycin low CSF or high?

Low

Azithromycin and roxithromycin concentarte in?

Immune cells

Azithromycin and clarithromycin ?

Active metabolities

Reversible 50s becteriostatic ?

Macrolide

Used for acne lyme desease and rickettsia

Doxycycline

Most tetracycline eliminated in renall but doxycycline ?

Stool

Good tissue penetration and low plasma concentration ?

Tigycycline

Reversible 30s becetriostatic ?

Tetracycline

Irreversible 30s becteriocidal ?

Aminoglycoside

Why aminoglycoside lacks activity against anaerob?

Require oxygen

Gentamycin + vancomycin?

Enterococcal endocarditis

Oral instestinal effect ?

Neomycin

IM and IV ?

Aminoglycoside

Low CSF penetration?

Aminoglycoside

50s orally or IV poor CSF penetration?

Clindamycin

Orally or Iv stop formation 70s ?

Oxazolidinones

Serotonin syndrome?

Oxazolidinones

Lenizolid elimiation by?

Renal

Tedizolid elimination by?

Hepatic