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1.Which of the following correctly defines the phases for suspensions and emulsions? A. Suspensions: liquid in liquid; Emulsions: solid in liquid B. Suspensions: gas in liquid; Emulsions: liquid in gas C. Suspensions: solid in liquid; Emulsions: liquid in liquid D. Suspensions: solid in solid; Emulsions: solid in liquid
C. Suspensions: solid in liquid; Emulsions: liquid in liquid
2.What is the official alcohol concentration percentage for Alcohol USP? A. 95% B. 70% C. 85% D. 100%
A. 95%
3.Each liter of Syrup USP contains which of the following precise ingredient amounts? A. 500 g sucrose and 500 mL of water B. 1000 g sucrose and 500 mL of water C. 850 mL sucrose and 463 g of water D. 850 g sucrose and 463 mL of water
D. 850 g sucrose and 463 mL of water
4.What is the typical range of alcohol content found in elixirs? A. 1% to 10% B. 5% to 40% C. 62% to 85% D. 15% to 80%
B. 5% to 40%
5.Spirits or essences typically contain an alcohol concentration ranging from: A. 62% to 85% B. 5% to 40% C. 15% to 80% D. 90% to 95%
A. 62% to 85%
6.The concentration of alcohol in tinctures generally varies within which range? A. 5% to 40% B. 62% to 85% C. 90% to 95% D. 15% to 80%
D. 15% to 80%
7.What is the primary function of antioxidant excipients in drug formulations? A. To enhance drug solubility and dissolution rates B. To act as an antimicrobial preservative C. To prevent or inhibit oxidation in the formulation D. To mask unpleasant tastes in oral liquids
C. To prevent or inhibit oxidation in the formulation
8.Which group of excipients should be avoided in newborns and infants under 6 months of age? A. Benzyl alcohol, Ethanol, Propylene glycol, and Polysorbate 20 and 80 B. Lactose, Starch, Talc, and Magnesium stearate C. Sodium chloride, Dextrose, Water for injection, and Glycerin D. Methylparaben, Propylparaben, Citric acid, and Sodium citrate
A. Benzyl alcohol, Ethanol, Propylene glycol, and Polysorbate 20 and 80
9.How does the Hydrophilic-Lipophilic Balance (HLB) value relate to a surfactant's properties? A. A higher HLB value means the surfactant is more lipophilic. B. HLB value has no correlation with the surfactant's hydrophilicity. C. A lower HLB value means the surfactant is more hydrophilic. D. A higher HLB value means the surfactant is more hydrophilic.
D. A higher HLB value means the surfactant is more hydrophilic.
10.What is a primary purpose of using cyclodextrins in a drug formulation? A. To decrease drug solubility and stability B. To increase the solubility of the drug formulation C. To function strictly as a buffering agent D. To lower the viscosity of liquid preparations
B. To increase the solubility of the drug formulation
11.Which cyclodextrin derivative is the most commonly used in pharmaceutical applications? A. Alpha-cyclodextrin B. Gamma-cyclodextrin C. Hydroxypropyl beta-cyclodextrin D. Methyl beta-cyclodextrin
C. Hydroxypropyl beta-cyclodextrin
12.Besides increasing solubility, what secondary property can cyclodextrins provide to a formulation? A. Masking bad taste B. Increasing particle size C. Acting as a primary colorant D. Providing a sustained-release polymer barrier
A. Masking bad taste
13.At what approximate alcohol concentration is a medication considered preserved? A. 5% or 10% B. 25% or 30% C. 50% or 60% D. 15% or 18%
D. 15% or 18%
14.According to the Noyes-Whitney equation, how can the dissolution rate of a dosage form be increased? A. By increasing the particle size of the drug compound B. By decreasing the particle size of the drug compound C. By decreasing the available surface area D. By increasing the viscosity of the solvent
B. By decreasing the particle size of the drug compound