Pt. 2- Transport Proteins and the Resting Membrane Potential

Malignant Hyperthermia

calcium-release channel that will not close

Erythermalgia

sodium channel that opens too easily

Myasthenia gravis

too few acetylcholine receptors

Secondary active transport

moves a substance against its gradient by borrowing the energy of another substance moving downs its gradient (no ATP is hydrolyzed by the transporter itself)

Symport vs Antiport

symport means both substances travel in the same direction, antiport means they travel in opposite directions

Receptor-mediated endocytosis

movement of large molecules across the membrane via vesicle (iron, LDL, hormones, antibodies)

Why is the cell membrane -70mV?

large negatively charged molecules are trapped inside, mainly K+ permeability maintained by the Na/K ATPase