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Acetylcholine (ACh)
Function: Enables muscle action, learning, and memory
Examples: With Alzheimer’s disease, ACh-producing neurons deteriorate
Dopamine
Function: Influences movement, learning, attention, and emotion
Examples: Oversupply is linked to schizophrenia; undersupply is linked to tremors and decreased mobility in Parkinson’s disease
Serotonin
Function: Affects mood, hunger, sleep, and arousal
Examples: Undersupply is linked to depression. Some drugs that raise serotonin levels are used to treat depression
Nonrepinephrine
Function: Helps control alertness and arousal
Examples: Undersupply can depress mood
GABA (gamma-aminobutyric acid)
Function: A major inhibitory neurotransmitter
Examples: Undersupply is linked to seizures, tremors, and insomnia
Glutamate
Function: A majory excitatory neurotransmitter; involved in memory
Example: Oversupply can overstimulate the brain, producing migraines or seizures
Endorphins
Function: Neurotransmitters that influence the perception of pain or pleasure
Examples: An oversupply of opioid drugs can suppress the body’s natural endorphin supply
Substance P
Function: Involved in pain perception and immune response
Examples: Oversupply can lead to chronic pain