Acetylsalicylic Acid (Aspirin) Drug Study

Vocabulary flashcards covering the drug profile of Acetylsalicylic acid (Aspirin), including drug class, indications, mechanism of action, dosages, adverse effects, contraindications, and nursing considerations.

Acetylsalicylic acid

The generic name for the antiplatelet drug with the trade name Aspirin.

Aspirin

The trade name for Acetylsalicylic acid.

Antiplatelet

The drug class for Acetylsalicylic acid (Aspirin).

Indications (Aspirin)

Prevent MI or stroke.

Mechanism of Action (Aspirin)

Blocks COX1 & COX2 and has irreversible effects on platelets.

Route / Administration (Aspirin)

PO (oral).

MI and Stroke Prophylaxis Dosage

$81\,\text{mg}$ of Aspirin.

Acute MI Dosage

$325\,\text{mg}$ of Aspirin.

Adverse Effects & Black Box (Aspirin)

GI upset (N/V, heartburn, ulcers, bleeding), life-threatening salicylate poisioning (no antidote), and neutropenia.

Salicylate poisioning

A life-threatening adverse effect of Aspirin for which there is no antidote.

Precautions / Contraindications (Aspirin)

Allergy, GI (ulcers), bleeding, anticoagulants therapy, renal impairment, and do not give to children with viral illnesses.

Nursing Considerations (Aspirin)

Stop one week prior to procedures (platelets), may take with food or mild dur to GI upset, DO NOT drink or use with other NSAID, monitor for bleeding, and avoid if pregnant.