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The four types of tissues
Epithelial, connective, muscle, nerve
What holds epithelial cells together?
Tight junctions and desmosomes
What supports epithelial tissue?
Connective tissue
What are the two parts of the basement membrane?
Reticular and basal laminae
Is epithelial tissue vascular or avascular?
Avascular
What is the difference between vascular and avascular?
Vascular = has blood vessels
Avascular = does NOT have blood vessels
What does innervated mean?
Supplied by nerve fibers
What does "regenerative" mean for epithelial tissue?
Rapidly replaces lost cells by cell division
What is the difference between simple and stratified epithelium?
Simple has one layer; stratified has two or more layers

What are the three shapes used to classify epithelial cells?
Squamous, cuboidal, and columnar
How do squamous, cuboidal, and columnar cells differ in shape?
Squamous = flat; cuboidal = cube-shaped; columnar = tall

What is the structure of simple squamous epithelium?
Single layer of flattened cells with disc-shaped nuclei and sparse cytoplasm
What are the functions of simple squamous epithelium?
Diffusion, filtration, friction-reducing lining
Where is simple squamous epithelium located?
Pic: air sacs of lung tissue
Kidney glomeruli, heart, blood vessels, lymphatic vessels, and serosae

What is the structure of simple cuboidal epithelium?
Single layer of cube-like cells with large, spherical central nuclei
What are the functions of simple cuboidal epithelium?
Secretion and absorption
Where is simple cuboidal epithelium located?
Kidney tubules, ducts and secretory portions of small glands, and ovary surface

What is the structure of simple columnar epithelium?
Single layer of tall cells with oval nuclei; many contain cilia
Goblet cells are often found in this layer
What are the functions of simple columnar epithelium?
Secretion and absorption
Where is nonciliated simple columnar epithelium located?
Digestive tract and gallbladder

Where is ciliated simple columnar epithelium located?
Small bronchi, uterine tubes, and some regions of the uterus
What is the structure of pseudostratified columnar epithelium?
Single layer of cells with different heights; some do not reach the free surface
Nuclei are seen at different layers
What is the function of pseudostratified columnar epithelium?
Secretion and propulsion of mucus
Where is pseudostratified columnar epithelium located?
Pic: trachea
Male sperm-carrying ducts (nonciliated) and trachea (ciliated)

What is the structure of stratified squamous epithelium?
Thick membrane composed of several layers of flat cells
What is the function of stratified squamous epithelium?
Protection of underlying areas subjected to abrasion
Where is stratified squamous epithelium located?
Pic: esophagus
Skin’s epidermis (keratinized); linings of esophagus, mouth, and vagina (nonkeratinized)

How common is stratified cuboidal epithelium?
Quite rare in the body
What are the structure and location of stratified cuboidal epithelium?
Typically two cube-shaped cell layers thick; found in some sweat and mammary glands
How widely distributed is stratified columnar epithelium?
Limited distribution in the body
Where is stratified columnar epithelium located?
Pharynx, male urethra, some glandular ducts, and transition areas between two other epithelial types
What is the structure of transitional epithelium?
Several cell layers; basal cells are cuboidal and surface cells are dome-shaped
What is the function of transitional epithelium?
Stretches to permit the distension of the urinary bladder
Where is transitional epithelium located?
Urinary bladder, ureters, and part of the urethra

What is a gland?
One or more cells that make and secrete an aqueous fluid
How are glands classified by their site of product release?
Endocrine or exocrine
How are glands classified by the number of cells forming the gland?
Unicellular or multicellular
What are endocrine glands?
Ductless glands that produce hormones
What do endocrine glands secrete?
Amino acids, proteins, glycoproteins, and steroids
How do exocrine glands differ from endocrine glands?
Exocrine glands are more numerous than endocrine glands
Where do exocrine glands secrete their products?
Onto body surfaces (skin) or into body cavities
What are examples of exocrine glands?
Mucous, sweat, oil, and salivary glands
What is the only important unicellular gland?
Goblet cell

What are multicellular exocrine glands composed of?
A duct and secretory unit
How are multicellular exocrine glands classified?
By simple or compound duct type and structure of their secretory units
What is the structure of skeletal muscle tissue?
Long, cylindrical, multinucleate cells with obvious striations

What is the function of skeletal muscle tissue?
Initiates and controls voluntary movement
Where is skeletal muscle tissue located?
Skeletal muscles that attach to bones or skin
What is the structure of cardiac muscle tissue?
Branching, striated, uninucleate cells interlocking at intercalated discs

What is the function of cardiac muscle tissue?
Propels blood into the circulation
Where is cardiac muscle tissue located?
Walls of the heart
What is the structure of smooth muscle tissue?
Sheets of spindle-shaped cells with central nuclei that have no striations

What is the function of smooth muscle tissue?
Propels substances along internal passageways, such as peristalsis
Where is smooth muscle tissue located?
Walls of hollow organs
What characterizes inflammation caused by tissue trauma?
Dilation of blood vessels, increased vessel permeability, redness, heat, swelling, and pain
What happens during tissue trauma?
Inflammation occurs, causing blood vessels to dilate and become more permeable
What happens during the organization and restored blood supply stage of tissue repair?
The blood clot is replaced with granulation tissue
What are the two possible outcomes of tissue repair?
Regeneration and fibrosis
What happens to the surface epithelium during tissue repair?
It regenerates and the scab detaches
What happens as fibrous tissue matures during tissue repair?
It begins to resemble the adjacent tissue
What is the result of tissue repair?
Fully regenerated epithelium with underlying scar tissue
What are the three primary germ layers?
Ectoderm, mesoderm, and endoderm
When are the three primary germ layers formed?
Early in embryonic development.
What do the three primary germ layers eventually specialize to form?
The four primary tissues
Which primary tissue arises from the ectoderm?
Nerve tissue
Which tissues arise from the mesoderm?
Muscle, connective tissue, endothelium, and mesothelium
Which structures mostly arise from the endoderm?
Most mucosae
Which germ layers can epithelial tissues arise from?
All three germ layers