16 Bile Acid Sequestrants Antilipidemic

Bile Acid Sequestrants example

Colesevelam (Welchol)

Bile Acid Sequestrants purpose

lower LDL, add-on to a statin

Bile Acid Sequestrants effects on the body

LDL used to make new bile acids (LDL falls moderately), triglycerides (may) rise

Bile Acid Sequestrants how is it given

with meal and liquid

T or F: Bile Acid Sequestrants is absorbed by the blood to take effect

F

Bile Acid Sequestrants dose and monitoring

Tablets (625 mg): 3.75 g _____, once or divided

Suspension: one 3.75 g packet daily with _____

daily, meal

Bile Acid Sequestrants indications

high LDL add-on therapy, Colesevelam also lowers blood sugar in type 2 diabetes

Bile Acid Sequestrants contraindications

triglycerides above 500 (mg); history of bowel obstruction/GI motility issue, pancreatitis from high triglycerides, PKU

Bile Acid Sequestrants side effects

constipation, gas, bloating, indigestion (dyspepsia), nausea

Bile Acid Sequestrants adverse effects

less absorption of vitamins ADEK, bowel obstruction/fecal impaction, higher triglycerides

Bile Acid Sequestrants client education

with meal and full glass of liquid, eat fiber and drink fluids to prevent constipation, never take power dry, 1 hr before or after any other drugs

Bile Acid Sequestrants client education report if

severe belly pain, vomiting, no stools