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Where are preauricular lymph nodes?
directly in front of the ear
Where are occipital lymph nodes?
at the back of the head, near the skull
Where are postauricular lymph nodes?
directly behind the ear, over the mastoid bone, where the sternocleidomastoid attaches
Where are the submandibular lymph nodes?
located beneath the body of the lower jawbone (mandible) within the submandibular triange
Where are the submental lymph nodes?
located beneath the chin, specifically within the submental triangle
Where are the anterior cervical lymph nodes?
small filters located in the front of the neck that help trap and fight off infections
Where are the posterior cervical lymph nodes?
located in the back of the neck along the posterior triangle and the external jugular vein
Where are the supraclavicular lymph nodes?
located in the hollow space just above the collarbone (clavicle), near the base of the neck
Where are the infraclavicular lymph nodes?
located just below the collarbone (clavicle), beside cephalic vein, in the groove between pectoralis major and deltoid muscles
Where are axillary lymph nodes?
located in the armpit that filter lymphatic fluid from upper limbs, breast tissue, shoulder, and chest wall
Where are the epitrochlear lymph nodes (cubital lymph nodes)?
in the subcutaneous fat on the inner (medial) side of the arm
Where are the inguinal lymph nodes?
in the groin area, specifically where the upper inner thigh meets the lower abdomen
Where are the popliteal lymph nodes?
in the popliteal fossa, behind the knee joint
Lymph
the fluid that enters the lymphatic vessels and is being transported back toward the cardiovascular system
Interstitial fluid
fluid found in spaces between cells
Lymphatic Capillaries
tiny, blind-ended lymphatic vessels that form web-like networks around blood capillary beds
Lymphatic Vessels
blind-ended vessels that collect lymph from tissues and return it to the bloodstream
Lymphokinesis
the flow or circulation of lymph through lymphatic vessels and lymph nodes
Lymph nodes
small, vaguely bean-shaped clusters of lymphatic tissue
Phagocytosis
cell-eating, cells ingest large particles such as bacteria, dead body cells, or cell fragments
Antigen presenting cells (APCs)
immune cells that ingest pathogens, process their antigens, and then display fragments on the surface
Mucosa Associated Lymphoid Tissue (MALT)
Lymphoid tissue along mucous membranes that are exposed to external environment and pathogens
Complement
Proteins (30 of them) produced by the liver that circulate in blood mostly in inactive forms - innate immunity
Membrane Attack Complex (MAC)
structure formed by several activated complement proteins on surface of target cell
Interferons
a type of cytokine (signaling protein) produced by several immune cells, including macrophages, dendritic cells, NK cells, and cells of adaptive immunity
B cells
A type of lymphocyte that develop and mature in bone marrow and reside in lymphoid organs
T cells
lymphocytes that form in the bone marrow but migrate to the thymus to mature
IgM
pentamer, first antibody secreted, potent in agglutination/precipitation
IgG
monomer, most abundant in serum
IgA
dimer, found in secretions, performs agglutination and neutralizaiton
IgE
Monomer, binds MAST cells and basophils, triggers deagglutination, driving inflammation in allergic reactions
IgD
monomer, found on B cell surfaces, helps in B cell sensitization and activation
Boyle’s law
pressure and volume are inversely related (when volume increases, pressure decreases)
Dalton’s law
explains how gases behave in a mixture (partial pressure=fraction of gas in mixture x total pressure)
Henry’s law
describes how well a gas dissolves in a liquid is proportional to both its partial pressure and its solubility in that liquid
Respiratory tract
a series of hollow passageways that transport air to and from the lungs
Respiration
overall process that supplies body cells with oxygen and removes carbon dioxide
Inspiration
when air moves into the lungs
Expiration
when air moves out of the lungs
Ventilation
the breathing process (first step of respiration)
Alveoli
terminal air sacs of the respiratory tract and primary sites of gas exchange in the lungs
Type I alveolar cells
(about 90%) very thin squamous cells that allow for rapid diffusion of gases
Type II alveolar cells
(about 10%) cuboidal cells that secrete surfactant, which reduces surface tension and helps alveolar collapse
Alveolar macrophages
phagocytes that “clean up” debris and pathogens, then migrate toward bronchioles to be removed
Respiratory membrane
an extremely thin barrier with a huge surface area that makes pulmonary gas exchange highly efficient
Spirometer
an instrument used to measure how much air a person moves in and out of the lungs with each breath
Upper respiratory tract
passageways from the nasal cavity to the larynx that includes the nose and nasal cavity, pharynx, and larynx
Lower respiratory tract
includes trachea, bronchi, bronchioles, and alveoli in lungs
Pressure gradient
a difference in pressure between two connected areas
Atmospheric pressure
the pressure exerted by the air in the atmosphere
Intrapulmonary pressure
the air pressure inside of the alveoli of the lungs
Intrapleural pressure
the pressure inside the pleural cavity
Parital pressure
each gas in the air exerts its own pressure, called partial pressure
Tidal volume
amount of air inspired or expired during normal, quiet breathing
Inspiratory reserve volume
max volume of air that can be forcibly inspired after a normal tidal inspiration
Expiratory reserve volume
max volume of air that can be forcibly expired after a normal tidal expiration
Residual volume
volume of air that remains in the lungs after the most forceful expiration
Vital capacity
the total volume of air that can move in and out of the lungs
Forced vital capacity
total volume of air that you can forcefully rapidly exhale from your lungs after taking a maximal deep breath
Inspiratory capacity
total amount of air that a person can inspire after a tidal expiration
Functional Residual Capacity
amount of air that is normally left in the lungs after a tidal (norma, quiet) expiration
Total lung capacity
total amount of air in the lungs, including exchangeable and nonexchangeable air
equation for inspiratory capacity
tidal volume (TV) + inspiratory reserve volume (IRV)
equation for Functional residual capacity
Expiratory reserve volume (ERV) + Residual Volume (RV)
equation for vital capacity
TV + IRV + ERV
Total lung capacity
TV + IRV + ERV + RV