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The right lung has how many lobes in the left lung has how many lobes
The right has three in the left has two
The trachea bifurcates at
T4 to T5
What are the common lymphatics of the lungs?
Intrapulmonary, bronchopulmonary, hilar, interlobar, mediastinal
The trachea extends from
The inferior border of the larynx to T5
Bronchi enter into the lung at the
Hilum
The mediastinum is the region between the lungs containing
Trachea, esophagus, thymus, lymph nodes, heart, and great vessels
What to create pathways from tumors to get to lymph
Hilum And mediastinum
What are some etiologic Factors of lung cancer
Smoking/secondhand smoke, older age, having previous lung cancer, air, pollution, radon, asbestos
Cigar and pipe smoking can be a risk for lung cancer, but Are usually associated with cancers of the
Aero digestive tract
True or false you can decrease the risk of developing lung cancer by quitting smoking at any age
True
What is the second leading cause of lung cancer and leading cause for non-smoker?
Radon
Abestos is linked to
Mesothelioma
What are some signs and symptoms of lung cancer?
Cough, hemoptysis, Dyspnea and chest pain, nerve symptoms, dysphasia, superior vena cava syndrome
Dyspnea and chest pain is a common symptom for involvement of the
Pleura, chest wall, or mediastinal structures
Tumors in the right lung or metastatic tumors in the right mediastinal notes may cause
Superior vena cava syndrome
Mesothelioma presents with
Pleural thickening, dyspnea, and chest pain as a result of plural fluid and invasion of the chest wall
What are paraneoplastic syndrome’s?
Secondary tumor effects, induction of signs and symptoms away from the primary site
Paraneoplastic syndrome’s are more associated with which type of lung cancer
Small cell lung cancer
A paraneoplastic lung cancer sign is
Hypertrophic osteoarthropathy, which is clubbing fingers
True or false there has been a decline in lung cancer incidence
True there has also been a decline in smoking rates
True or false worldwide lung cancer is the most common cancer
True
Risk for lung cancer increases with
Age
Most patient with lung cancer are aged
65 and older
Is lung cancer more common in women or men?
Way more common in women could be due to trends in smoking between genders
Do blacks or whites have a higher risk for a lung cancer
Blacks
What type of cancer is the leading cause of death in the US?
Lung cancer
Mesothelioma arises from
The mesothelial cells that line the plural cavity and can affect visceral imp prior or pleura
What is the prognosis of mesothelioma?
Prognosis is poor with a five year survival rate of 16% for stage one a and stage four is less than 1%
What is known as the oat cell intends to occur more centrally and behave similar to large cell carcinoma
Small cell lung cancer
Is small cell or non-small cell more prone to metastasis early?
Small cell lung cancer
What are the common sub types of non-small cell lung cancer?
Adenocarcinoma, squamous cell carcinoma, large cell carcinoma
What is the most common histology sub type of non-small cell lung cancer in the US?
Adenocarcinoma and is usually found in the peripheral lung
What is the most common non-small cell lung cancer subtype worldwide?
Squamous cell carcinoma
What is the most common non-small cell lung cancer subtype found in non-smokers
Adenocarcinoma
Which non-small cell lung cancer histology subtype is found in smokers
Squamous cell carcinoma
What is the least common non-small cell lung cancer subtype
Large cell carcinoma
Which imaging is preferred for the work up of lung cancer?
Chest x-ray
Which imaging is the most valuable for studying staging and therapeutic planning for lung cancer?
CT
What is used to examine the airway to identify obstruction and obtained tissue sample of the lungs?
Bronchoscopy
If a lesion is too peripheral for a broncoscopy what is used
Find needle aspiration
What type of biopsy may be necessary for mesothelioma?
Pleural biopsy
What are the treatment options for mesothelioma?
Surgery, radiation, therapy, and chemotherapy
Surgery includes a pleurectomy
And the chemo is platinum based
Adjuvant radiation therapy is controversial for mesothelioma because
Of lung toxicity
What is the general treatment for an early stage lung cancer?
Surgery consisting of a lobectomy, but can do a pneumonectomy where the entire lung is removed
What is the most effective chemo for lung cancer?
Cisplastin
Were advanced disease, lung cancer, what is used?
Palliative radiation therapy for controlling hemoptysis
What are the three routes of spread for lung cancer?
Local, which is direct Intrathoracic spread
Regional, which is lymphatic spread
Distant, which is hematogenous spread
Lung cancer commonly metastasize is to which area
The brain
Can also spread to the lung liver and bone, especially vertebrae and adrenal gland
Which histologic sub type of one cancer has a high incidents for Mets especially skip Mets
Adenocarcinoma
The most common lymph nodes involved for lung cancer is
Hilar then goes to media Steindl, then supraclavicular
The path of lymph node spread for the lungs is
Intrapulmonary, hilar, the inferior mediastinal nodes (Subcarinal), Superior mediastinal (Retro tracheal, pre-tracheal, paratracheal)
Staging for non-small cell cancer and small cell lung cancer is based on
Size and tumor extension
Staging for mesothelioma is based on
Tumor size and extension
Prognosis for lung cancer is based on
Performance status, stage, and weight loss
Is the prognosis for non-small cell lung, cancer better or small cell lung cancer?
Non-small cell lung cancer
What is the five year survival rate from lung cancer?
16%