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T/F: Odontogenic infections are caused by normal oral bacteria flora
True
Infections are almost always ___________
Polymicrobial
Single primary organism usually not identifiable via routine testing
50–60% involve both aerobic and anaerobic bacteria
Odontogenic infections involve what type of bacteria?
Aerobic and anaerobic gram positive cocci
Anaerobic gram negative rods
Aerobic bacteria are most commonly ________
Viridans type streptococci (streptococcus viridans)
What are facultative organisms?
Survive with or without oxygen
Aerobic bacteria initiate progression of ______ to _______ infections
Superficial to deeper
Anaerobic bacteria are most commonly ________
Bacteroides spp
followed by prevotella spp or peptostreptococcus spp
What is the progression of invasion?
Initial invasion
Anaerobic shift and tissue breakdown
Expanding abscess increases hydrostatic pressure
Initial invasion: Bacterial penetrate deeper soft tissues and _________
Fascial (potential) spaces
Initial invasion: Spread is facilitated by _____, which breaks down hyaluronic acid
Hyaluronidase
Initial invasion: enables movement through ________ tissue
Subcutaneous
Anaerobic shift and tissue breakdown: bacterial metabolism _____ pH, creating acidic environment
Lowers
This is why we use carbocaine for infected areas - does not contain epinephrine or other vasoconstrictors, and its chemical properties (lower pH) match infected tissue
Anaerobic shift and tissue breakdown: Favors ______, leading to liquefaction necrosis
Anaerobes
Anaerobic shift and tissue breakdown: Breakdown of _____ and formation of ______
WBCs, microabscesses
Anaerobic shift and tissue breakdown: Microabscesses may _______ into a clinical abscess
Coalesce
Expanding abscess increases hydrostatic pressure: _______ blood vessels, causing ischemia
Compresses
(Makes it harder for abx to reach abscess)
Expanding abscess increases hydrostatic pressure: Leads to expansion of ______ within abscess cavity
Necrotic tissue
What are the main sources of odontogenic infection?
Endodontic (necrotic pulp)
Periodontal (deep pockets, pericoronitis)
what is the subperiosteal plane?
anatomical space between the gum tissue and the jawbone where dental infections can accumulate to form a subperiosteal abscess, a localized collection of pus that requires surgical drainage and antibiotics to prevent the spread of infection to surrounding tissues
Infection erodes through what cortical bone in subperiosteal plane?
Facial or lingual
Infection erodes through facial or lingual cortical bone into which plane?
Subperiosteal
What does infection spread depend on?
Tooth location
Bone thickness
Muscle attachments
(Infection takes the path of least resistance)
Infection from maxillary molars erodes through what?
Facial cortex (thinner facial bone)
Infection from mandibular molars erodes through what?
Buccal or lingual cortex (thinner, apices lingual)
What are potential spaces most often created by?
Infection or surgery
What does spread of infection depend on?
Relation to muscle attachments
What does an infection that spreads buccally depend on?
Buccinator muscle attachment
What does an infection that spreads lingually depend on?
Mylohyoid muscle attachment
If infection of a maxillary molar is below the buccinator attachment, where will it go? (path of least resistance)
Vestibular space
If infection of a maxillary molar is above the buccinator attachment, where will it go? (path of least resistance)
Buccal space
If infection of a mandibular molar is below the buccinator attachment, where will it go? (path of least resistance)
Buccal space
If infection of a mandibular molar is above the buccinator attachment, where will it go? (path of least resistance)
Vestibular space
(lingual) If infection of a mandibular molar is below the mylohyoid attachment, where will it go? (path of least resistance)
Submandibular space
(lingual) If infection of a mandibular molar is above the mylohyoid attachment, where will it go? (path of least resistance)
Sublingual space
Where does lingual infection of a maxillary molar go?
Palatal space
Where do endodontic infections originate?
The pulp
Where do bacteria and byproducts travel through to lead to bone erosion and abscess formation? (for endo origin)
The apex
Where do periodontal infections originate?
The periodontium
Typically involve perio tissues leading to purulence adjacent to teeth and PDL
Which infection origin (endo or perio) is more likely to cause bone erosion?
Endo
T/F: Periodontal origin infections spread directly into potential spaces
True (but less common)
What are the 4 stages of infection?
Inoculation (edema)
Cellulitis
Abscess
Resolution
What stage of infection?
Day 0-3
Soft red swelling
Mildly tender
Inoculation (edema)
What stage of infection?
Day 3-5
Firm (indurated)
Diffuse
Painful swelling
must be treated
Cellulitis
What stage of infection?
Anaerobes dominate, purulence forms → localized swelling (fluctuance)
Abscess
What stage of infection?
Drainage occurs
Healing begins
Resolution
What is the most common clinical presentation of odontogenic infection?
Vestibular space abscess of endodontic origin
T/F: An odontogenic infection will not rupture and drain spontaneously
False (It MAY drain spontaneously)
Odontogenic infections can form ______ to oral cavity or ______ to skin
Fistula, sinus tract
Why do we always put a drain into odontogenic infections?
They may reclose and reform abscess if not resolved (bc oral cavity heals really fast so incision closes quickly)
What are the 3 core infection management factors?
Control the source of infection
Establish drainage
Mobilize the host defense system
What is an example of eliminating the source of infection?
Removing an infected tooth, endo tx, perio tx
What is key once an abscess forms?
Surgical intervention
What must you do to any purulent collection?
Drain it
Mobilize host defense system, but remember antibiotics are _______, not primary tx
Adjunctive
What are the principles of infection management?
Determine severity
Evaluate host defense
Determine treatment setting
Surgical treatment
Medical treatment
Antibiotic choice
Antibiotic administration
Reevaluation
What is in the physical exam?
Swelling
Pain
Trismus
Fever
Airway compromise
Red flag symptom: How do we directly check for dyspnea?
Listen for if they have difficulty breathing
Red flag symptom: How do we directly check for dysphagia/odontophagia?
Ask if they have pain with swallowing
Red flag symptom: How do we directly check for dysphonia?
Listen for voice change
Interpreting history: chronic pain may mean ______
Necrotic pulp or periodontal disease
Interpreting history: pain migration may mean ______
Deeper space involvement
Interpreting history: >30 days may mean ______
It's a chronic, contained infection
Interpreting history: rapid onset may mean _______
Aggressive infection or immune compromise
Interpreting history: persistent infection post treatment may mean _______
Aggressive case
What is a concerning heart rate?
>100 bpm (tachycardia)
What is a concerning respiratory rate?
>20 breaths/min (tachypnea)
What is a concerning body temperature?
>101 degrees F (systemic involvement!!)
What is a concerning peripheral oxygen saturation level?
SpO₂ <95% (possible airway compromise!!)
How to check for general appearance and airway? (4 things)
1. Observe pt on entry
2. Fatigue, drooling, voice change
3. Listen for stridor
4. Assess swelling, asymmetry, and erythema
Fatigue, drooling, and voice change may mean _______
Severe infection
if you hear stridor it may mean _______
Airway obstruction risk
harsh, high-pitched, monophonic sound that occurs during breathing (usually in) due to narrowed or partially blocked upper airways. It is a symptom of an underlying airway disorder rather than a diagnosis itself (wheeze in lower airway, expiration)
Palpation and consistency of swelling: doughy (thickened and soft) may indicate ______
Early infection (edema), mild tenderness
Palpation and consistency of swelling: indurated (thickened, hard, inflexible) may indicate ______
Cellulitis, diffuse and tender
Palpation and consistency of swelling: fluctuant (moving in waves, thick balloon) may indicate ______
Abscess, localized and less tender
Is it possible for multiple consistencies in swelling to exist?
Yes
Always identify if swelling is ______ or ________
Vestibular or gingival
Is vestibular or gingival swelling worse?
Vestibular (bc it could've moved anywhere)
Swelling in the temple area means which space is involved?
Superficial temporal
Deep temporal
Swelling in the orbit means which space is involved?
Periorbital space
Swelling in the nasolabial area (loss of nasolabial fold) means which space is involved?
Canine space
Swelling in the cheek area means which space is involved?
Buccal space
Swelling in the angle of the mandible means which space is involved?
Masseteric space
Lateral pharyngeal space
Swelling of the inferior border of mandible and lateral neck means which space is involved?
Submandibular space
Swelling of the inferior border of mandible and midline neck means which space is involved?
Submental space
What is normal maximum incisal opening (MIO)?
>40mm
What might trismus indicate?
Deep space infection (but can also be from guarding)
T/F: Severity of swelling correlates with infection severity
True
A swelling may be absent with deep infections, what intervention would be required in this case to identify definitively (when you have other signs such as dysphagia, odynophagia, dysphonia, dyspnea)?
CT scan
What else can limited opening affect?
Intraoral access
Anesthesia
_____mm opening suggests severe infection
<15mm
What is one way to look for signs of airway compromise?
Deviation of uvula
Common modalities of imaging are PA, pan, cone beam CT. They can show tooth abnormality, but we need a _______ to show infection
CT scan
What imaging system has a broad view and has minimal discomfort?
Panoramic
What imaging system has a detailed tooth/root view and minimal radiation?
PA
What is a 3D imaging system that is useful for unclear sources?
Cone beam CT (***not diagnostic****)
What imaging system identifies deep space infections and requires this with IV contrast?
Medical grade CT
Surgical management and healing is dependent on ________ host defense system
Intact
Compromised host defense requires aggressive treatment and ______
Antibiotics
What medical comorbidities are metabolic?
Diabetes
Alcoholic liver disease
What medical comorbidities are immune system disorders?
Leukemia/lymphoma
HIV