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-artan
angiotensin II receptor blocker
-olol
beta blocker
-pril
ACE inhibitor
-azosin
alpha blocker
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adrenergic inhibitors
-pine
calcium channel blockers
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direct vasodilators
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direct vasodilators
-ide
loop diuretics
-ide
thiazide diuretics
mechanism of action for -artan
prevents angiotensin II from binding to receptors in blood vessel walls = vasodilation & increase sodium and water excretion
mechanism of action for -olol
blocks beta-1 adrenergic receptors = decrease CO and reduce sympathetic vasoconstriction; decreases renin secretion
mechanism of action for -pril
preventions angiotensin I from turning into angiotensin II; prevents vasoconstriction & sodium and water retention
mechanism of action for -azosin
blocks alpha adrenergic effects producing vasodilation; decreases SVR & BP
mechanism of action for adrenergic inhibitors
decrease SNS stimulation; decreases SVR & BP
mechanism of action for -pine
increase sodium excretion and cause vasodilation by preventing calcium into cells; smooth muscle relaxation = decreased SVR & BP
mechanism of action for direct vasodilators
relax vascular smooth muscle & reduce SVR
mechanism of action for loop diuretics
inhibit NaCl reabsorption into loop of Henle = increased NaCl & water excretion and reduced SVR
mechanism of action for thiazide diuretics
inhibit NaCl reabsorption in the distal convoluted tubule + increased NaCl & water secretion and decreased SVR
nursing considerations for -artan
can take 3-6 weeks to take full effect
nursing considerations for -olol
monitor bp & pulse before taking medication
hold if hr is <60 bpm
less effective bp reduction in african american patients
nursing considerations for -pril
ASA & NSAIDs may reduce effectiveness
avoid with K sparing diuretics
can increase serum creatinine
can cause dry hacking cough
nursing considerations for -azosin
take at bedtime to prevent orthostatic hypotension
nursing considerations for adrenergic inhibitors
avoid sudden discontinuation to reduce withdrawal symptoms
chew gum or candy for dry mouth
reposition slowly
nursing considerations for -pine
avoid grapefruit
use cautiously with CHF patients
nursing considerations for direct vasodilators
use for hypertensive crisis
monitor for hypotension
nursing considerations for loop diuretics & thiazide diuretics
monitor for orthostatic hypotension
monitor for electrolyte imbalance
monitor I&O, edema, lung sounds, weight