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Blood draw locations
jugular vein
lateral saphenous vein
cephalic vein
medial saphenous vein (cats)
What is a blood draw location for cats only
medial saphenous vein
CBC tube color
purple
purple top tube
contains EDTA anticoagulant
evaluates white blood cells, red blood cells, red blood cell components, and platelets
what is the anticoagulant in a purple top tube
ethylene diamino tetra acetate
Red Blood Cell RBC function
carry oxygen from lungs to tissues using hemoglobin (protein)
What is an increase in RBC called
Erythrocytosis
What causes erythrocytosis
methylene blue toxicity
dehydration
what is decreased RBC called
anemia
What is the causes of anemia
blood loss
decreased RBC production
PCV/Hematocrit stands for
packed cell volume
normal PCV/Hematocrit range
35-55%
Increased PCV (>55%) caused by
dehydration
splenic contraction
hypoxemia
Decreased PCV value (<35%) cause
Anemia
Over hydration
What are WBC also called
leukocytes
What is the function of leukocytes
protect the body against infectious or foreign causes
what is increased WBC called
leukocytosis
What causes leukocytosis
infection
inflammation
what is decreased WBC called
Leukopenia
What causes leukopenia
viral infection
decreased bone marrow production
Neutrophils function
functions in inflammation by phagocytosis and killing bacteria
what is increased neutrophils called
neutrophilia
what causes neutrophilia
inflammation (acute or chronic)
Infection (toxic changes or bands present)
excitement/stress
what is decreased neutrophils called
neutropenia
what causes neutropenia
viral infection
intense inflammation (especially bacterial)
endotoxemia and severe hypothermia
lymphocytes function
mediate immune response
what is increased lymphocytes called
lymphocytosis
what causes lymphocytosis
infection
excitement/stress (especially cats)
cancers (leukemia, lymphoma)
hypoadrenocorticism (addisons)
what is decreased lymphocytes called
lymphopenia
what causes lymphopenia
acute infections (especially viral)
glucocorticoid use
immunodeficiency
monocytes function
become macrophages when in tissues and fluid to kill bacteria and fungi
what is increased monocytes called
monocytosis
what causes monocytosis
inflammation (acute or chronic)
stress
some cancers (leukemia)
What is a decrease in monocytes called
monocytopenia
what causes monocytopenia
not clinically significant
eosinophils function
attack parasites, inflammation of skin, respiratory disease (worms, wheezes, and weird diseases)
what is increased eosinophils called
eosinophilia
what causes eosinophilia
Parasites (intestinal, fleas)
Allergic reactions
Hypoadrenocorticism (Addison's disease)
what is a decreased eosinophil called
eosinopenia
what causes eosinopenia
stress
acute inflammation
rarely clinically significant
basophils function
can be seen with immune reactions (rarely seen in healthy animals)
what is increased basophils called
basophilia
what causes basophilia
allergic reactions (food, insect sting)
parasites
some cancers (mast cell neoplasm)
is decreased basophils clinically significant
no
what are platelets also known by
thrombocytes
what are the function of platelets or thrombocytes
required for inflammation and wound healing
normal platelet/ thrombocyte range
150,000-400,000 uL
what is increased thrombocytes called (platelets)
thrombocytosis
what causes thrombocytosis
exercise
epinephrine release
increased production- inflammation, iron deficiency
hyperadrenocorticism or cushings disease
what is decreased thrombocytes called (platelets)
thrombocytopenia
what causes thrombocytopenia
acute or severe blood loss
immune mediated destruction
infectious disease (canine distemper, canine parvo, tick borne disease)
Chemistry blood work tube color
red top tube
red top tube
evaluates organ and tissue function
what is apart of CBC or purple top tube
RBC, WBC, PCV, Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils, Platelets
what is apart of chemistry or red top tubes
total protein, albumin, globulin, blood urea nitrogen (BUN), Creatinine, Alanine Aminotransferase (ALT), Alkaline phosphatase (ALP), blood glucose (BG), Sodium (Na+), Potassium (K+)
total protein function
maintain osmotic pressure of blood, important to hemostasis, transport molecules such as drugs and hormones, and help with inflammation and immune response
are there multiple types of serum proteins?
Yes different types of serum proteins help determine underlying cause
Albumin function
predominant protein within blood
what causes increased albumin
dehydration
what causes decreased albumin
kidney disease
burns
hemorrhage
decreased production
liver disease
acute inflammation
severe gastrointestinal disease
dilution (fluid accumulation disorders like Congestive heart failure)
Globulin function
wide function
what causes increased globulins
liver disease
FIP
cancers (multiple myeloma, lymphoma)
Dehydration
What causes decreased globulins
hemorrhage
gastrointestinal protein loss
Blood Urea Nitrogen (BUN) function
concentration of urea in blood- Kidney function
what causes increased BUN (Blood urea nitrogen)
dehydration
kidney disease
urinary obstruction
GI hemorrhage
what causes decreased BUN (blood urea nitrogen)
Liver failure
severe polyuria/polydipsia
Creatinine function
waste product of muscle creatine excreted through urine- Kidney function
what causes increased creatinine
kidney disease
what causes decreased creatinine
muscle loss
thin body condition
SDMA
more specific and more sensitive to kidney disease
early indicator
Alanine Aminotransferase (ALT) function
enzyme in liver cell cytoplasm
what causes increased ALT (alanine aminotransferase)
liver cell damage/inflammation
liver disease
medications (steroids, carprofen, phenobarbital)
toxin
Alkaline Phosphatase (ALP) function
enzyme found in liver, bone, and other tissues
increased ALP (alkaline phosphatase) causes
liver disease
gallbladder disease
medications (steroids, phenobarbital)
bone growth, fracture repair, osteo-
cushings disease
Blood Glucose function
sugar in blood used for energy production
normal blood glucose range
60-125
increased blood glucose is called
hyperglycemia
hyperglycemia causes
diabetes mellitus
stress/excitement
postprandial (post mean)
Decreased blood glucose called
hypoglycemia
hypoglycemia causes
neonatal/juvenile infrequent feedings
insulin overdose
insulinoma
liver disease
sepsis
Sodium (Na+) function
extracellular fluid cation
Increased Na+ causes
fluid loss (vomiting diarrhea)
kidney disease
decreased Na+ causes
end stage kidney disease
GI loss (vomiting, diarrhea)
Overhydration
congestive heart failure
Potassium (K+) function
intracellular cation essential for action potentials in muscles
increased K+
urinary obstruction
hypoadrenocorticism or Addisons disease
diabetic ketoacidosis
decreased K+ causes
increased loss (vomiting, diarrhea)
IV fluid Dilution
How many views are recommended everytime for radiographs
3
what three views are reccomended everytime
right lateral
left lateral
ventral/dorsal
how to interpret radiographs
(always interpret entire thing)
crainal to caudal approach
systems approach
Black to white radiograph
gas
fat
soft tissue
mineral/bone
metal
white to black radiograph
metal
bone/mineral
soft tissue
fat
gas
how many opacities are there on radiographs
5
roentgen sign
1-size 2-shape 3-location 4-number 5-margins 6-opacity
what is the roentgen sign
method for describing radiographic abnormalities