PHA 329 Estrogen/Progesterone Systemic Effects

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Last updated 4:11 PM on 9/7/26
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9 Terms

1
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Systemic Effects of Estrogen? (Reproductive)

  • Growth, development, maintenance of reproductive organs

  • Promotes growth of milk ducts in pregnancy

  • Vaginal lubrication; libido


2
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Systemic Effects of Estrogen? (Bone)

  • inhibits bone resorption (↑bone mineral density)

  • promotes widening of pelvis


3
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Systemic Effects of Estrogen? (Liver)

  • Increased synthesis of clotting factors (pro-coagulation)

  • ↑ HDL (good cholesterol), ↓ LDL (bad cholesterol); increase cholesterol excretion through bile


4
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Systemic Effects of Estrogen? (Renal)

Na+/water reabsorption

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Systemic Effects of Estrogen? (Dermatologic)

decreased sebum production

6
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Systemic Effects of Estrogen? (Other)

  • lowers body temperature

  • decreases milk secretion

  • mood regulation

  • promotes female-pattern fat deposition


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Systemic Effects of Progesterone? (Maintenance of pregnancy)

  • Forms cervical mucus plug (protects uterus)

  • Suppresses uterine contractions


8
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Systemic Effects of Progesterone? (Renal)

Na+/water reabsorption

9
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Systemic Effects of Progesterone? (Other)

  • Increases body temperature

  • Increases appetite & weight gain

  • Decreases libido

  • Constipation

  • Stimulates growth of milk-producing glands (alveoli) in pregnancy