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GI Tract (alimentary canal)
Continuous tube from mouth to anus that facilitates digestion and absorption of food and nutrients
Accessory digestive organs
Organs that assist in digestion but not part of GI tract. Help with mechanical digestion (chewing) and/or chemical digestion (enzymes, bile, etc)
Salivary glands
Secrete saliva into GI tract which chemically breaks down food on a small scale
Main functions of digestive systems
Ingestion, Motility, Secretion, Digestion, Absorption, Elimination
Mucosa (GI Tract Wall)
Innermost layer of GI tract wall that directly faces lumen that shields the body from home
Submucosa
Connective tissue layer of the GI tract wall containing larger blood vessels, lymphatic vessels and nerves
Muscularis Externa
Responsible for mixing and propulsion in GI tract wall; comprised of two muscular layers that produce motility using peristalsis and sphincters
Serosa/adventitia
Outermost layer of GI tract wall that provides covering and support. Serosa reduces friction and adventitia anchors portions of GI tract to surrounding structures
Enteric nervous system role in digestion system
Network of neurons within GI tract wall that detects changes within the GI tract wall and coordinates changes
Autonomic nervous system role in the digestive system
Parasympathetic- rest and digest; relaxes many sphincters open
Sympathetic- fight or flight; contracts many sphincters close
Peritoneum
Serous membrane that lines abdominopelvic cavity
Mesentary
anchor the intestines to the posterior abdominal wall while supplying them with blood, lymphatics, and nerves
Mucosa associated lymphatic tissue MALT
acts as a primary defense system that monitors and fights germs entering through the body's mucous membranes
Upper GI Tract Organs
Oral Cavity and salivary glands, pharynx, esophagus, stomach, duodenum
Bolus
Food + saliva
Pharynx
Bolus enters during swallowing, assisted by saliva and mucus which lubricate
Esophagus
Transports bolus from pharynx to stomach via peristalsis
Regions of the oral cavity
Vestibule (where zyn goes) and oral cavity proper (where food goes)
Palate
Roof of oral cavity that elevates during swallowing to close nasopharynx
Pharynx
Muscular pathway shared by respiratory and digestive systems
Directs food from oral cavity to esophagus
What kind of cells do the oropharynx and laryngopharynx have and why
Nonkeratinized stratified squamous to protect against friction
Esophagus
Muscular tube that takes bolus to the stomach via peristalsis, closes when empty
Upper (superior) esophageal sphincter
Located between pharynx and esophagus, normally closed and prevents air from entering esophagus while breathing- relaxes during swallowing
Lower (inferior) esophageal sphincter
Located between esophagus and stomach, relaxes as bolus approaches stomach and closes after to limit gas reflux
Swallowing phases
Oral phase (voluntary) which involves chewing
Pharyngeal phase (involuntary) where soft plate elevates to close nasopharynx
Swallowing apnea
Breathing temporarily stops during breathing
Four regions of the stomach
Cardia, Fundus, Body, Pylorus
Rugae
Gastric folds of the stomach mucosa that allows that stomach to stretch
Cells that line the stomach
Simple Columnar epithelium cells that are exposed to a high acidic environment that are replaced rapidly
Surface mucous cells
secretes alkaline mucin
Mucous neck cell
secretes a much less alkaline mucin
Parietal Cells
secrete intrinsic factor (important for B12 absorption) and hydrochloric acid to create stomachs acidic environment (H+ and Cl- are secreted separately)
Chief Cells
secrete pepsinogen, inactive precursor of pepsin to be later activated in stomach by HCl
Pepsin role
Digests protein to smaller pepsides
G-cells
Endocrine cells that secrete gastrin (hormone) into the blood for increased gastric secretion and motility
Cephalic phase of stomach activity
Brain knows food is coming and stomach gets ready
Gastric phase of stomach activity
Food arrives to stomach, stomach expands, neural reflexes, increased secretion and concentration
Intestinal phase
Small intestine sends signal to slow down; decreased motility and secretion and gastric emptying is slowed
Small intestine
Organ in GI tract responsible for completing chemical digestion and most absorption
Duodenum
First part of small intestine that connects to the stomach that is a major site for continuing chemical digestion. Acts as a mixing chamber and receives chyme and bile + pancreatic juices to assist
Jejunum
Longest portion of small intestine which is the primary absorber
Circular folds
“Speed bumps” in the jejunum that cause friction to slow food down
Villi
Structure in the jejunum that increase absorption and surface activity and contain blood capillaries (absorb water soluble nutrients) and lymphatic capillaries (absorb fat soluble nutrients)
Microvilli
Brush like projections in villi that contain enzymes to assist chemical digestion
Ileum
Last region of the small intestine that is crucial in vitamin B12 absorption via intrinsic factor released by parietal cells
Biliary Apparatus
Network of ducts that transport bile from the liver to gallbladder to the duodenum
Pancreatic ducts
Main and accessory (backup)
Hepatic portal system
takes blood from GI tract to liver
Bile
Yellow green fluid containing bile salts, bicarbonate, cholesterol, pigments, and water
Bile emulsification
Bile salts digest lipids mechanically
Gallbladder
stores bile, not a gland as it doesn’t produce
Pancreas
Organ that breaks everything down. Endocrine functions through hormones and exocrine functions through pancreatic juice which contains digestive enzymes
Large intestine
Absorbs remaining water and electrolytes and compacts and stores fecal material
Cecum
First portion of large intestine