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Contact Inhibtion
Shuts off cell division when new cells come into contact with old cells. Prevents overproduction of cells.
Cyclin
Regulatory protein produced by the cell during the G1 phase. Its job is to regulate and stimulate cell division. Accumulates in the cell and when there is enough, it is pushed into the S phase. Substrate for enzyme CDK
CDK
Enzyme proteins that are naturally produced in the cell. When bound with cyclin, they promote a chain of reactions. Leads to production of MPF
MPF
Accumulation of MPF’s signal to begin cell division. Cyclin is converted to MPF by CDK
Carcinoma
Cancer of epithelial tissue
Sarcoma
Cancer of connective tissue
Myeloma
Tumor of the bone marrow