OMFPR 15 - Pulpal and Periapical Pathology & Inflammatory Lesions of Jaws (Dr. Pabla & Dr. Lerman)

inflammation

What is the most common disease process that a dentist encounters?

imaging/radiographs

What play a key role in identifying and determining the extent of involvement in bone?

periapical inflammatory disease

What is an inflammatory response to pathogenic microorganisms and necrotic pulp (caries, trauma) that is restricted to the root apex?

- Periodontal disease

- Pericoronitis

What are two extensions of inflammation into bone from soft/gingival tissue?

supporting structures of tooth

Periodontal disease is inflammation of what?

crown of partially erupted tooth

Pericoronitis is inflammation of what?

osteomyelitis

What is an extension of inflammation into bone marrow?

necrotic pulp

Caries and trauma can develop into what?

periapical inflammatory disease

Necrotic pulp can develop into what?

osteomyelitis

Periapical inflammatory disease can develop into what?

periapical abscess

What is an example of acute periapical disease?

periapical granuloma

What is an example of chronic periapical inflammatory disease?

- Osteomyelitis

- Periapical cyst

What two things can a periapical granuloma develop into?

- Widened PDL space

- Loss of lamina dura

What are two radiographic signs of apical periodontitis?

increased radiolucency

Rarefying osteitis leads to what radiographically?

rarefying osteitis

What condition?

- Chronic inflammation associated with a

NON-VITAL TOOTH

- Radiolucent presentation due to removal of bone

- Sequela of an acute episode

- Includes abscess, granuloma or radicular cyst

radiolucent

Rarefying osteitis has what radiographic presentation?

rarefying osteitis

What condition?

Cannot differentiate on a radiograph --> need histology section

How do you differentiate abscess, granuloma, or radicular cyst?

- Focal sclerosing osteitis

- Condensing osteitis

Sclerosing osteitis has what other two names?

sclerosis

What means "hardening" of bone?

increase in radiopacity of bone

Sclerosis leads to what radiograph changes?

- Widened PDL

- Sclerosis

What are two defects that the arrows are pointing to?

Carious exposure of pulp

ID the condition:

Root fracture

ID the condition:

Diagnosis is based on clinical signs and symptoms

Very early lesions show no radiographic evidence because there is inadequate time for changes in calcified content (i.e.1-2 weeks, or 12%- 15% to 2/3rd of bone turnover).

How can you make a diagnosis of an early lesion?

early (involving pulp, no changes in bone)

The white arrow is showing what type of lesion?

chronic (loss of lamina dura, apical radiolucency and surrounding sclerotic bone reaction)

The blue arrow is showing what type of lesion?

- Loss of apical lamina dura

- Widening of apical PDL space

What are two early changes in periapical inflammatory disease?

early change (apical periodontitis #30)

What type of change is seen in this radiograph?

early change (apical periodontitis #21)

What type of change is seen in this radiograph?

early change (apical periodontitis #17-18)

What type of change is seen in this radiograph?

early change (apical periodontitis #14)

What type of change is seen in this radiograph?

- Apical to root apex

- Adjacent to accessory canal/root fracture/perforation

Periapical inflammatory disease can be located where?

away from root apex

If a periapical lesion enlarges, the epicenter moves where?

apical rarefying osteitis

What condition is present in this radiograph?

apical rarefying osteitis

What condition is present in this radiograph?

well defined

Well defined or poorly defined?

poorly defined

Well defined or poorly defined?

little

Early stages of periapical inflammatory disease has what effect on adjacent bone?

sclersoing osteitis

What is bone deposition around area of rarefaction called?

- Thicker trabeculae

- Increase in marrow spaces

Periapical inflammatory disease alters trabecular bone pattern and marrow spaces in what ways?

true

T/F: Periapical inflammatory disease can cause periosteal new bone formation and perforation of bone border

halo sign

What is a key sign of periapical inflammatory disease where there is an elevation/displacement of the floor of the maxillary sinus usually affecting maxillary posterior teeth?

halo sign

What are the arrows pointing to?

halo sign

What are the arrows pointing to?

periostitis/onion skin

What are the arrows pointing to?

Periostitis and mucositis

What are the arrows pointing to?

maxillary sinus floor periostitis/mucositis

What condition?

rarefying and sclerosing osteitis

Majority of periapical inflammatory disease show a combination of what?

rarefying

Is this radiolucent inflammation classified as rarefying or sclerosing?

sclerosing (added bone)

This radiopaque area is classified as rarefying or sclerosing?

sclerosing (added bone)

Is this radiolucent inflammation classified as rarefying or sclerosing?

apical rarefying osteitis

The arrows are pointing at the loss of apical lamina dura and periapical radiolucency, what is the differential diagnosis?

healthy (no loss of lamina dura, submandibular gland fossa- normal anatomy)

What is the differential diagnosis?

Sclerosing osteitis

(Widening of PDL space, Periapical radiopaque area, Non vital tooth)

Sclerosing osteitis or dense bone island?

Dense bone island

(No widening of PDL space, Periapical radiopaque area, Vital tooth)

Sclerosing osteitis or dense bone island?

Sclerosing osteitis

Sclerosing osteitis or dense bone island?

- Widening of PDL space

- Periapical radiopaque area

- Non vital tooth

Dense bone island

Sclerosing osteitis or dense bone island?

- No widening of PDL space

- Periapical radiopaque area

- Vital tooth

A) Rarefying osteitis

What is the differential diagnosis?

A) Rarefying osteitis

B) Maxillary sinus pneumatization

C) Mucus retention pseudocyst

D) Sclerosing osteitis

B) Maxillary sinus pneumatization

What is the differential diagnosis?

A) Rarefying osteitis

B) Maxillary sinus pneumatization

C) Mucus retention pseudocyst

D) Sclerosing osteitis

C) Mucus retention pseudocyst

What is the differential diagnosis?

A) Rarefying osteitis

B) Maxillary sinus pneumatization

C) Mucus retention pseudocyst

D) Sclerosing osteitis

osteomyelitis

What condition?

- Inflammation of bone

- Extension of inflammation from periapical region to the marrow space, cortex, cancellous portion of bone & periosteum.

Pyogenic organisms can reach bone marrow:

- Abscessed teeth

- Post- surgical infection

- Trauma

- Hematogenous spread

osteomyelitis

These are predisposing conditions of what?

- Malnutrition

- Diabetes

- Leukemia

- Anemia

- Alcoholism

- HIV

- Diseases with reduced vascularity in bone:

- - Paget disease of bone

- - Florid osseous dysplasia

- - Osteopetrosis

- - Fluorosis

C) Garre's Osteomyelitis

All of the following are synonyms for osteomyelitis EXCEPT...

A) Acute osteomyelitis

B) Acute suppurative osteomyelitis

C) Garre's Osteomyelitis

D) Acute pyogenic osteomyelitis

E) Proliferative periostitis

F) Periostitis Ossificans

acute osteomyelitis

Which type of osteomyelitis is most common in the mandible, premolar-molar area?

acute osteomyelitis

The following are characteristic clinical features of what?

- Pain

- Swelling

- Redness

- Fever

- Purulent discharge

- Mobility in involved teeth

chronic osteomyelitis

Characteristic features of what?

- Sequela of inadequately treated acute phase

- May arise de novo

CRMO (chronic recurrent multifocal osteomyelitis)

What type of osteomyelitis also occurs in long bones of children, has pain and swelling?

- Synovitis (inflammatory arthritis)

- Acne (pustulosa)

- Postulosis (psoriasis)

- Hyperostosis (acquired)

- Osteitis

What does SAPHO syndrome stand for?

chronic

CRMO and SAPHO are what types of osteomyelitis?

A. SAPHO syndrome

A 35-year-old woman presents with pustular lesions on her palms and chronic pain near the sternoclavicular joint. Imaging reveals hyperostosis and osteitis. Which condition is most likely?

A. SAPHO syndrome

B. Chronic recurrent multifocal osteomyelitis

C. Rheumatoid arthritis

D. Chronic bacterial osteomyelitis

True

T/F: Clinical features of chronic osteomyelitis are intermittent recurrent pain and swelling

acute osteomyelitis

What type of osteomyelitis? Radiographic features :

- No radiographic manifestation in early stages

- Imaging features vary depending on the stage of disease

Acute osteomyelitis

(periphery: poorly defined, non-corticated, gradual transition to normal trabeculae)

What phase of osteomyelitis?

acute osteomyelitis (internal structure)

What phase of osteomyelitis?

- Decrease in density of bone, loss of sharpness of trabeculae

- Localized or scattered regions of radiolucency, ill defined periphery

Acute osteomyelitis

A periapical radiograph of the right mandible shows an ill-defined radiolucent area with loss of trabecular pattern and decreased bone density. The patient reports pain, swelling, and fever. Which condition is most consistent with these findings?

Initial blurring of bony trabeculae

In the early radiographic stage of acute osteomyelitis of the mandible, what is a characteristic finding?

moth-eaten appearance of acute osteomyelitis

These arrows are pointing at what?

acute osteomyelitis, mixed radiolucent/radiopaque areas

The moth eaten appearance is associated with what?

sequestrae

What are islands of necrotic bone that vary in size?

sequestrae

What is the black arrow pointing at?

periosteal reaction

What is the white arrow pointing at?

periosteal reaction (increased bone density)

What is the black arrow pointing at?

sequestra

What is the white arrow pointing at?

acute (multiple sequestrae)

What phase of osteomyelitis does this show?

CBCT

What is the imaging method of choice for osteomyelitis

Periosteal reaction (acute osteomyelitis)

A radiograph of the mandible shows concentric layers of new bone formation parallel to the cortex, producing an "onion-skin" appearance. What is the diagnosis?

Alternating cycles of periosteal bone deposition and resorption

The "onion-skin" appearance seen in acute osteomyelitis results from which process?

New bone formation parallel to the cortex

How does early periosteal involvement in acute osteomyelitis form in relation to the cortex?

periosteal reaction

What is happening here?

onion skin

Proliferative periostitis is also known as what?

fistula

What defect?

Destruction of buccal cortex (ill defined radiolucent area in the mandible)

What occured?

Pathologic fracture

Osteomyelitis caused what to occur?

proliferation reaction

What is the primary response of diffuse sclerosing osteomyelitis?

diffuse sclerosing osteomyelitis (chronic osteomyelitis)

What type of osteomyelitis?

- Sclerotic appearance of involved bone

- Subperiosteal bone deposition

- Slight jaw enlargement

- Involves large segment of jaw

diffuse sclerosing osteomyelitis (chronic osteomyelitis)

What is the differential diagnosis of the left angle-ramus of mandible?

SAPHO Syndrome

A patient's pano is shown and presents with wrist symptoms. What is the differential diagnosis?

osteoradionecrosis (ORN)

What is the condition?

- Radiation induced damage to bone : resulting from exposure to therapeutic doses of radiation

- Doses above 50 Gy cause hypocellularity and hypovascularity

- Clinically exposed necrotic bone

- Radiologic changes similar to Osteomyelitis