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Evolution
A change in the allele frequencies of a population over time.

Allele
A variant or version of a gene.

Gene pool
A description of every allele for every gene locus in a population.

Mutation
A potentially heritable source of new alleles that can be neutral, deleterious, or beneficial.

Gene flow
The movement of individuals and their alleles between populations.

Genetic drift
A random change in allele frequencies within a population due to chance occurrences.

Bottleneck effect
A catastrophic event that drastically reduces population size and alters allele frequencies, lowering diversity.

Founder effect
A change in allele frequencies when a small subset of a population colonizes a new area.

Natural selection
The only mechanism known to produce adaptive evolution, requiring differential reproductive success, heritability, and variation.

Fitness
A measure of how many copies of an individual's alleles are passed to the next generation.

Direct fitness
An individual's alleles passed to subsequent generations through personal reproduction.

Indirect fitness
An individual's alleles passed to subsequent generations through the reproduction of relatives.

Neutral variation
Genetic variation that does not confer a selective advantage or disadvantage.

Heterozygote advantage
When heterozygous individuals have higher relative fitness than homozygotes, such as sickle-cell carriers resisting malaria.

Frequency-dependent selection
Selection in which the fitness of a phenotype depends on its frequency relative to other phenotypes in the population.
