gastric secretion

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6 Terms

1
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cephalic phase (reflex phase)

  • takes place before food enters stomach (triggered by the smell, taste, thought, or sight of food)

  • signals to brain from other senses to increase gastric secretion

  • loss of appetite surpress cephalic reflex


2
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gastric phase

  • lasts 3-4 hours

  • triggered by local neural and hormonal mechanisms by entry of food

  • stimulates parasympathetic neurons to release digestive hormones (acetylcholine. gastrin, enteroendocrine G cells, HCl)

  • activates smooth muscle contractions


3
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intestinal phase

  • has both excitatory and inhibitory elements

  • duodenum has major role in regulating the stomach and its emptying


4
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duodenum’s role in stomach emptying:

  • intestinal mucolsal cells release hormone called enteric (intestinal) gastrin, which furter excites gastric juice secretion


5
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enterogastric reflex

inhibits secretion

closes the pyloric sphincter to block additional chyme from entering the duodenum

6
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mucosal barrier

  • protects the stomach from self digestion

  • thick lated of bicarbonate rich mucous which neutralize acid

  • epithelial cells meet at tight junctions making it impermeable

  • stem cells are nearby to quickly replace damaged epithelium