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Pulmonary edema — Giveaways
Severe dyspnea, crackles, orthopnea; severe cases have pink frothy sputum.
Pulmonary edema — Differentiator
Fluid collects inside alveoli, often from left-sided CHF; unlike mucus-related COPD.
Pulmonary edema — Scenario
A patient with heart disease wakes gasping, cannot lie flat, has crackles and pink foam at the mouth.
Congestive heart failure (CHF) — Giveaways
Poor cardiac pumping, dyspnea, fatigue, crackles, sometimes neck-vein distention and leg edema.
Congestive heart failure (CHF) — Differentiator
Pump failure causes fluid backup; pulmonary edema is a lung manifestation of CHF, not the whole disease.
Congestive heart failure (CHF) — Scenario
A patient with prior heart attacks has swollen ankles, nighttime breathlessness and crackles.
Chronic obstructive pulmonary disease (COPD) — Giveaways
Long smoking history, progressive dyspnea, prolonged expiration, wheezes or rhonchi.
Chronic obstructive pulmonary disease (COPD) — Differentiator
Broad chronic airflow-obstruction category encompassing emphysema and chronic bronchitis; not fully reversible.
Chronic obstructive pulmonary disease (COPD) — Scenario
A longtime smoker uses home oxygen and has gradually worsening breathlessness and prolonged exhalation.
Emphysema — Giveaways
Thin appearance, barrel chest, pursed-lip breathing, tripod positioning, reduced breath sounds.
Emphysema — Differentiator
Alveolar walls and capillary beds are destroyed; unlike chronic bronchitis, often little sputum.
Emphysema — Scenario
A thin older smoker leans forward, breathes through pursed lips and has a barrel-shaped chest.
Chronic bronchitis — Giveaways
Chronic productive cough with excess mucus, rhonchi or wheezing, possible cyanosis.
Chronic bronchitis — Differentiator
Mucus production and airway irritation dominate; emphysema mainly destroys alveoli.
Chronic bronchitis — Scenario
A longtime smoker has a persistent mucus-producing cough, noisy breath sounds and bluish lips.
Asthma — Giveaways
Episodic wheezing, prolonged expiration, dyspnea and chest tightness after triggers.
Asthma — Differentiator
Bronchiolar spasm, swelling and mucus; episodes may be reversible with bronchodilators, unlike fixed COPD.
Asthma — Scenario
A teen develops wheezes and prolonged expiration after exposure to a cat and has an inhaler.
Status asthmaticus — Giveaways
Severe prolonged asthma attack not relieved by usual treatments; fatigue and possible silent chest.
Status asthmaticus — Differentiator
Unlike an ordinary asthma flare, obstruction persists and respiratory failure is imminent.
Status asthmaticus — Scenario
A child has used a prescribed rescue inhaler repeatedly but becomes exhausted with minimal air movement.
Pneumonia — Giveaways
Fever, productive cough, pleuritic pain, dyspnea; crackles or rhonchi possible.
Pneumonia — Differentiator
Lung infection; fever and infectious symptoms favor it over cardiogenic pulmonary edema.
Pneumonia — Scenario
An older adult develops fever, cough with sputum and sharp pain on inspiration over several days.
Pulmonary embolism — Giveaways
Abrupt dyspnea, pleuritic chest pain, tachycardia, hypoxia; recent immobility or surgery.
Pulmonary embolism — Differentiator
Clot blocks pulmonary blood flow; unlike pneumonia, onset is often sudden without infectious prodrome.
Pulmonary embolism — Scenario
A patient two days after hip surgery suddenly has sharp chest pain, tachypnea and cyanosis.
Spontaneous pneumothorax — Giveaways
Sudden one-sided pleuritic pain and dyspnea with reduced breath sounds.
Spontaneous pneumothorax — Differentiator
Air enters pleural space without external trauma; tension type additionally impairs circulation.
Spontaneous pneumothorax — Scenario
A previously well tall young adult suddenly feels sharp one-sided chest pain and shortness of breath.
Pleural effusion — Giveaways
Progressive dyspnea with diminished breath sounds from fluid around a lung.
Pleural effusion — Differentiator
Fluid lies in pleural space outside lung; pulmonary edema fills alveoli within lung.
Pleural effusion — Scenario
A patient with chronic heart failure gradually becomes short of breath with reduced sounds at a lung base.
Croup — Giveaways
Child with barking seal-like cough, hoarse voice, inspiratory stridor, often low fever.
Croup — Differentiator
Viral upper-airway inflammation with a barky cough; epiglottitis more often drools and lacks barking cough.
Croup — Scenario
A toddler has a hoarse seal-bark cough and noisy inhalation that worsens overnight.
Epiglottitis — Giveaways
Sudden severe sore throat, high fever, drooling, tripod posture and stridor.
Epiglottitis — Differentiator
Swollen epiglottis threatens abrupt obstruction; drooling and toxic appearance distinguish from croup.
Epiglottitis — Scenario
A very ill child sits upright drooling, refuses to swallow and has high-pitched inspiration.
Bronchiolitis (often RSV) — Giveaways
Child under 2 years with wheezing, nasal secretions, cough, retractions and feeding difficulty.
Bronchiolitis (often RSV) — Differentiator
Inflammation of tiny bronchioles in infants; differs from barking-cough upper-airway croup.
Bronchiolitis (often RSV) — Scenario
An eight-month-old in winter has cough, nasal mucus, rapid breathing and poor feeding.
Pertussis — Giveaways
Repeated forceful coughing fits followed by inspiratory whoop; sometimes vomiting after coughing.
Pertussis — Differentiator
Distinctive paroxysmal cough/whoop rather than barking cough of croup.
Pertussis — Scenario
A young child has repeated coughing spells and then draws a noisy whooping breath.
Tuberculosis (TB) — Giveaways
Persistent cough, night sweats, fever, weight loss, sometimes blood in sputum.
Tuberculosis (TB) — Differentiator
Chronic infectious course with weight loss and night sweats; unlike acute pneumonia.
Tuberculosis (TB) — Scenario
A patient reports weeks of coughing, fatigue, weight loss and night sweats.
Cystic fibrosis — Giveaways
Young patient with recurrent lung infections, thick mucus and chronic respiratory difficulty.
Cystic fibrosis — Differentiator
Inherited disorder with abnormally thick secretions; not smoking-related COPD.
Cystic fibrosis — Scenario
A teenager with lifelong respiratory problems has recurrent infections and thick airway secretions.
Anaphylaxis — Giveaways
Rapid hives, facial or tongue swelling, wheezing or stridor, possible hypotension.
Anaphylaxis — Differentiator
Systemic life-threatening allergic reaction involving breathing or circulation; unlike local allergy.
Anaphylaxis — Scenario
Minutes after a bee sting, a patient develops hives, wheezing, swollen lips and BP 82/48.
Mild localized allergic reaction — Giveaways
Itching, localized redness, hives or swelling without breathing trouble or shock.
Mild localized allergic reaction — Differentiator
No systemic airway or cardiovascular compromise; unlike anaphylaxis.
Mild localized allergic reaction — Scenario
After an insect sting, a patient has itching and a small rash but normal breathing and BP.
Acute coronary syndrome (ACS) — Giveaways
Pressure-like chest discomfort, diaphoresis, nausea, dyspnea; possible radiation to arm or jaw.
Acute coronary syndrome (ACS) — Differentiator
Umbrella for acute coronary ischemia, including unstable angina and MI; field findings overlap.
Acute coronary syndrome (ACS) — Scenario
An adult has new crushing chest pressure, sweating and nausea at rest.
Angina pectoris — Giveaways
Chest pressure on exertion or stress that may improve with rest or prescribed nitroglycerin.
Angina pectoris — Differentiator
Temporary myocardial ischemia without infarction; MI causes sustained muscle injury.
Angina pectoris — Scenario
A man develops chest pressure climbing stairs that resolves after resting.
Acute myocardial infarction (MI) — Giveaways
Persistent pressure/crushing chest pain, sweating, nausea and possible referred jaw or arm pain.
Acute myocardial infarction (MI) — Differentiator
Heart-muscle death from prolonged ischemia; may not resolve with rest or nitroglycerin.
Acute myocardial infarction (MI) — Scenario
A patient has 35 minutes of chest pressure radiating to left arm with cold sweating.
Cardiogenic shock — Giveaways
Hypotension, weak pulse, altered mentation, cool clammy skin after major cardiac dysfunction.
Cardiogenic shock — Differentiator
Pump failure causes shock despite possible normal blood volume; unlike hemorrhagic shock.
Cardiogenic shock — Scenario
Hours after severe chest pain, a patient becomes pale, confused and hypotensive with a weak pulse.
Hypertensive emergency — Giveaways
Severely elevated BP with acute organ symptoms such as headache, neurologic deficits or chest pain.
Hypertensive emergency — Differentiator
End-organ injury matters more than a BP number alone; uncomplicated hypertension lacks these findings.
Hypertensive emergency — Scenario
A patient has extreme hypertension with sudden confusion and chest discomfort.
Aortic dissection — Giveaways
Sudden severe tearing chest or back pain, sometimes unequal peripheral pulses or BP.
Aortic dissection — Differentiator
Tear within aortic wall; distinct from MI's typical pressure sensation, though overlap occurs.
Aortic dissection — Scenario
A hypertensive patient describes abrupt ripping pain from chest to back with unequal arm pulses.
Abdominal aortic aneurysm (AAA) — Giveaways
Sudden abdominal or back pain, possible pulsatile abdominal mass and shock if ruptured.
Abdominal aortic aneurysm (AAA) — Differentiator
Enlarged aorta can rupture internally; unlike appendicitis, rapid collapse and back pain may occur.
Abdominal aortic aneurysm (AAA) — Scenario
An older patient has sudden deep abdominal/back pain, pale skin and falling blood pressure.
Ventricular fibrillation (VF) — Giveaways
Unresponsive, pulseless arrest; disorganized ventricular electrical activity; shockable rhythm.
Ventricular fibrillation (VF) — Differentiator
No effective contraction or cardiac output; unlike ventricular tachycardia, no organized complexes.
Ventricular fibrillation (VF) — Scenario
A patient suddenly collapses pulseless, and an AED advises shock for chaotic rhythm.
Ventricular tachycardia (VT) — Giveaways
Very rapid ventricular rhythm causing palpitations, weakness, chest pain or hypotension.
Ventricular tachycardia (VT) — Differentiator
May have a pulse or be pulseless; VF has completely chaotic activity without output.
Ventricular tachycardia (VT) — Scenario
A patient feels sudden racing heartbeat and dizziness and becomes hypotensive.
Cardiac tamponade — Giveaways
Chest trauma with shock, possibly muffled heart sounds and distended neck veins.
Cardiac tamponade — Differentiator
Blood in pericardial sac compresses heart; tension pneumothorax instead traps air in pleura.
Cardiac tamponade — Scenario
After a penetrating chest wound, a patient becomes hypotensive with distended neck veins.
Commotio cordis — Giveaways
Sudden collapse and cardiac arrest immediately after precisely timed blunt blow to chest.
Commotio cordis — Differentiator
Electrical arrest without necessarily severe structural damage; unlike myocardial contusion.
Commotio cordis — Scenario
A young baseball player is struck by a ball over the heart and immediately collapses pulseless.
Ischemic stroke — Giveaways
Sudden facial droop, arm weakness, speech difficulty or other focal deficit.
Ischemic stroke — Differentiator
Blocked cerebral artery, not bleeding; cannot reliably distinguish stroke type from symptoms alone.
Ischemic stroke — Scenario
A woman suddenly develops right arm weakness, facial droop and slurred speech.
Hemorrhagic stroke — Giveaways
Sudden severe headache, vomiting, altered consciousness and possible focal weakness.
Hemorrhagic stroke — Differentiator
Bleeding inside/around brain; severe abrupt headache suggests it, but field diagnosis is uncertain.
Hemorrhagic stroke — Scenario
A patient describes the worst headache of life and suddenly collapses with vomiting.
Transient ischemic attack (TIA) — Giveaways
Sudden stroke-like weakness, speech or vision changes that resolve.
Transient ischemic attack (TIA) — Differentiator
Temporary loss of cerebral blood flow with symptoms resolving; still warns of future stroke.
Transient ischemic attack (TIA) — Scenario
A patient's one-sided weakness and garbled speech disappear before EMS arrival.
Generalized tonic-clonic seizure — Giveaways
Whole-body stiffening and rhythmic jerking, impaired awareness, possible incontinence, postictal confusion.