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215 Terms
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Component that distinguishes the cell wall of Gram-positive bacteria from Gram-negative bacteria,Thick peptidoglycan layer and teichoic acids.
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Structural characteristic of Gram-negative bacterial cell walls absent in Gram-positive cells,Outer membrane containing lipopolysaccharides (LPS).
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Specific substance in Mycobacteria cell walls that necessitates acid-fast staining,Mycolic acids.
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Constituents of a virus's genetic material,"Either DNA or RNA, but never both."
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Enzyme used by retroviruses to synthesize DNA from an RNA template,Reverse transcriptase.
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The specific target cell of the Human Immunodeficiency Virus (HIV),CD4+ T cells.
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Term for a virus that specifically infects bacterial cells,Bacteriophage.
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Bacteriophage life cycle characterized by immediate replication and host cell destruction,Lytic cycle.
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Bacteriophage life cycle where viral DNA integrates into the host genome without immediate lysis,Lysogenic cycle.
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Intracellular signaling molecule increased by Cholera toxin to trigger Cl− secretion,Cyclic AMP (cAMP).
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Mechanism of action of the Botulinum toxin at the neuromuscular junction,It blocks the release of Acetylcholine (ACh).
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Primary effect of Tetanus toxin on the nervous system,It blocks the release of inhibitory neurotransmitters.
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Evolutionary theory suggesting mitochondria and chloroplasts originated from bacteria,Endosymbiotic theory.
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Sedimentation coefficient of ribosomes found within mitochondria and chloroplasts,70S.
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Primary method of reproduction in prokaryotic organisms,Binary fission.
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The three primary mechanisms of horizontal gene transfer in bacteria,"Transformation, transduction, and conjugation."
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"Circular, extra-chromosomal DNA molecules in bacteria often carrying resistance genes",Plasmids.
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Specific bacterial structure targeted by Penicillin to inhibit growth,Peptidoglycan crosslinking in the cell wall.
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Specific target of bacterial ribosome inhibitors,The 70S ribosome (composed of 50S and 30S subunits).
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Composition of prions,Infectious proteins containing no nucleic acids.
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Composition of viroids,Infectious naked RNA molecules that primarily affect plants.
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Distinction between 'antigenic drift' and 'antigenic shift' in viruses,"Drift involves small mutations, while shift involves genome reassortment leading to pandemics."
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Genome type of the SARS−CoV−2 virus,Positive-sense RNA.
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Original biological function of the CRISPR−Cas9 system in bacteria,An adaptive immune system used to defend against viral infections.
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Direction in which DNA polymerase reads the template strand,3′→5′.
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Direction in which DNA polymerase synthesizes a new DNA strand,5′→3′.
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Enzyme responsible for sealing nicks between Okazaki fragments,DNA ligase.
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Coding characteristic of eukaryotic mRNA compared to prokaryotic mRNA,"Eukaryotic mRNA is monocistronic, while prokaryotic mRNA is polycistronic."
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Primary eukaryotic enzyme responsible for synthesizing mRNA,RNA polymerase II.
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Length of Okazaki fragments in eukaryotic cells,100–200 base pairs (bp).
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Length of Okazaki fragments in prokaryotic cells,1000–2000 base pairs (bp).
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The standard start codon and the amino acid it encodes,"AUG, which codes for Methionine (Met)."
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The three universal stop codons,"UAA, UAG, and UGA."
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Phenomenon allowing flexible base pairing at the third position of a codon,Wobble hypothesis.
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Sedimentation coefficient of the functional eukaryotic ribosome,80S (composed of 60S and 40S subunits).
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Term for catalytic RNA molecules,Ribozymes.
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Sequence required for the initiation of translation in prokaryotes,Shine-Dalgarno sequence.
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Sequence required for the initiation of translation in eukaryotes,Kozak sequence.
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Amino acids that are highly concentrated in histone proteins,Lysine and Arginine.
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Function of Histone H1,It acts as a linker histone to stabilize the nucleosome structure.
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Transcriptional status of euchromatin vs heterochromatin,"Euchromatin is transcriptionally active, while heterochromatin is dense and inactive."
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The physical diameter of the DNA double helix,2nm.
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The number of base pairs contained in one full turn of the DNA helix,10.5bp.
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The specific amino acid substitution in Sickle-cell anemia,Glutamate (Glu) is replaced by Valine (Val) in the β-globin chain.
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Mechanism of mutation in Huntington’s disease,CAG repeat expansion.
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Mechanism of mutation in Fragile X syndrome,CGG repeat expansion.
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Definition of Vmax in enzyme kinetics,The maximum velocity of an enzymatic reaction at saturating substrate concentrations.
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Definition of the Michaelis constant (Km),The substrate concentration at which the reaction velocity is half of Vmax.
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Effect of a competitive inhibitor on Km and Vmax,"Km increases, but Vmax remains unchanged."
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Effect of a noncompetitive inhibitor on Km and Vmax,"Vmax decreases, but Km remains unchanged."
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Optimal pH for the protein-digesting enzyme pepsin,Approximately 2.
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Optimal pH for the pancreatic enzyme trypsin,Approximately 8.
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Thermodynamic parameter that enzymes cannot change,Gibbs free energy change (ΔG).
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Primary mechanism by which enzymes increase reaction rates,By lowering the activation energy.
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Protein tag used to signal the degradation of proteins by the proteasome,Ubiquitin.
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Primary source of NADPH in the cell,The Pentose Phosphate Pathway (PPP).
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Total net ATP yield from the complete oxidation of one palmitate (C16) molecule,106ATP.
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Net products of glycolysis from one molecule of glucose,"2ATP, 2NADH, and 2 pyruvate."
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Net energy products of the Krebs cycle per molecule of glucose,"2ATP, 6NADH, and 2FADH2."
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Final electron acceptor in the mitochondrial electron transport chain,Oxygen (O2).
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The specific wavelength absorbed by Photosystem II,680nm.
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The specific wavelength absorbed by Photosystem I,700nm.
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Energy requirements of the Calvin cycle to produce one molecule of glucose,18ATP and 12NADPH.
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"Process where Rubisco binds to O2 instead of CO2, reducing photosynthetic efficiency",Photorespiration.
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Source of the oxygen gas (O2) produced during photosynthesis,Water (H2O).
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Normal pH range of human arterial blood,7.35–7.45.
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Average total blood volume in a healthy human adult,Approximately 5L.
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Comparison of oxygen affinity between fetal hemoglobin (HbF) and adult hemoglobin (HbA),HbF has a higher oxygen affinity than HbA.
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Description of the Bohr effect,High CO2 or H+ concentrations decrease hemoglobin's affinity for O2.
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Description of the Haldane effect,The oxygenation of hemoglobin promotes the dissociation of CO2.
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Relative binding strength of carbon monoxide (CO) to hemoglobin compared to O2,CO binds approximately 200 times more strongly than O2.
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Shape of the oxygen dissociation curve for myoglobin,Hyperbolic.
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Shape of the oxygen dissociation curve for hemoglobin,Sigmoidal.
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Average lifespan of a red blood cell,Approximately 120 days.
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Normal range for white blood cell (WBC) count per microliter,5000–10000 /μL.
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Only class of immunoglobulin (Ig) capable of crossing the placenta,IgG.
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"Primary class of immunoglobulin found in bodily secretions (saliva, tears, breast milk)",IgA.
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Class of immunoglobulin primarily involved in allergic reactions and parasitic defense,IgE.
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Distribution of MHCI molecules in the human body,Found on all nucleated cells.
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Distribution of MHCII molecules in the human body,Found only on antigen-presenting cells (APCs).
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Standard resting membrane potential of a neuron,−70mV.
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Threshold potential required to trigger an action potential,−55mV.
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Stoichiometry of the Na+/K+ pump,"3Na+ ions out, 2K+ ions in."
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Type of nerve impulse conduction that occurs at the Nodes of Ranvier,Saltatory conduction.
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The major inhibitory neurotransmitter in the brain,GABA.
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The major inhibitory neurotransmitter in the spinal cord,Glycine.
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The primary excitatory neurotransmitter in the central nervous system,Glutamate.
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Subunit of troponin that binds to calcium ions to initiate muscle contraction,Troponin C.
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Protein that physically blocks the myosin-binding sites on actin at rest,Tropomyosin.
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Essential molecule required for the detachment of the myosin head from actin,ATP.
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Functional structures present in cardiac muscle but absent in skeletal muscle,Intercalated discs and gap junctions.
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The volume of air inspired or expired during a normal breath at rest,Tidal volume (approx. 500mL).
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The maximum amount of air that can be expired after a maximum inspiration,Vital capacity (approx. 4.5L).
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The volume of air remaining in the lungs after a forced expiration,Residual volume (approx. 1.2L).
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Primary method of CO2 transport in the blood,"As bicarbonate ions (HCO3−), accounting for 70% of transport."
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Function and cellular source of pulmonary surfactant,Lowers alveolar surface tension; secreted by type II pneumocytes.