Psyc Meds

What to monitor with antidepressants

manic activation, take daily, risk of serotonin syndrome

What category… Fluoxetine (prozac)

SSRI

What category… Sertraline (Zoloft)

SSRI

What category… Citalopram (celexa)

SSRI

What category… Escitalopram (Lexapro)

SSRI

What category… Paroxetine (paxil)

SSRI

What category… Fluvoxamine (luvox)

SSRI

MOA SSRI

block serotonin reuptake inc availability

What are SSRIs used for

1st line antidepressants

Common side effect SSRIs

GI, insomnia, sex, weights

Severe side affects SSRI

QT prolonging, serotonin syndrome

PNA SSRIs

takes. 4-6 weeks, monitor for SI, teach S/S of serotonin sydnrome

What category…Venafaxine (effexor)

SNRI

What category… Duloxetine (cymbalta)

SNRI

What category… Desvenlafaxine (pristiq)

SNRI

MOA SNRI

block reuptake of serotonin and norepinephrine

Common side effects SNRI

sweating, agitation, in BP, anxiety

Severe side effects SNRI

inc risk of withdrawl

PNA SNRI

Monitor BP, taper slowly

What category… Amitriptyline (Elavil)

TCA

What category… Nortriptyline (pamelor)

TCA

What category… Imipramine (tofranil)

TCA

MOA TCA

block serotonin and noreprine reuptake

Common side effects TCA

dry mouth, sedation, weight gain

Severe side effects TCA

Cardiotoxic in overdose

PNA TCA

monitor ECG in overdose, use caution in SI pt. educate on OD risk

What is buspirone (Buspar) used for

anxiety

MOA buspirone (Buspar)

unknwon does not affect GABA

Common side effects buspirone (Buspar)

dizzy, drowsy, nausea, headace

PNA buspirone (Buspar)

take as scheduled, take with food

What are the -pam’s used for

anxiety

MOA Benzodiazepines

enhance GABA activity, CNS depression

Common side effects Benzodiazepines

sedation, memory and corrdination issues

Severe side effects Benzodiazepines

risk of abuse, withdrawl with seizures

PNA Benzodiazepines

avoid alc and driving, short term or prn, slowly taper

Bupropion (wellbutrin) is also known as

happy, horny, skinny pill

Bupropion (wellbutrin) MOA

inhibits reuptake of dopamine and noreprine

What is Bupropion (wellbutrin) used for

depression

Common side effects Bupropion (wellbutrin)

insomnia, agitation, weight loss

Sever side effects Bupropion (wellbutrin)

risk of seizures

PNA Bupropion (wellbutrin)

avoid in patients with seizure or eating disorders, admin in morning

What is prazosin (minipress) used for?

Nightmares associated with PTSD

MOA prazosin (minipress)

alpha 1 blocker that reduces sympathetic activity

Common side effects prazosin (minipress)

orthostatic hypotension

PNA prazosin (minipress)

admin at bedtime, education

What is lithium used for

mood stabilization, bipolar

MOA Lithium

modulates neurotransmitter singaling

Common side effects Lithium

tremor, diarrhea, wekaness

Severe side effects Lithium

confusion, seizures

What is the therapeutic level lithium

0.6-1.2

PNA lithium

therapeutic level, monitor renal function, hydrate

What is Lamotrigine (lamictal) used for

mood stabilization, anticonvulsant

MOA Lamotrigine (lamictal)

stabilzes neuronal membranes

Common side effects Lamotrigine (lamictal)

stevens-johnsons rash

PNA Lamotrigine (lamictal)

titrate slowly, discontinue if rash develops, not for pregnant

What is divalproex sodium (depakote) used for

mood stabilzation, anticonvulsant

MOA divalproex sodium (depakote)

inc GABA levels

Common side effects divalproex sodium (depakote)

weight gain, sedation

Severe side effects divalproex sodium (depakote)

hepatotoxicity

PNA divalproex sodium (depakote)

monitor liver function and platelets, NO babies

What is Carbamazepine (tegretol) used for

mood stabilzation, anticonvulsant

MOA Carbamazepine (tegretol)

blocks sodium channels

Common side effects carbamazepine (tegretol)

risk of agranulocytosis

PNA Carbamazepine (tegretol)

monitor CBC, report fever or sore throat

What is haloperidol (haldol)

1st gen atipsychotics

What is chlorpromazine

1st gen antipsychotics

MOA 1st gen antipsychotics

block dopamine receptors

Common side effects 1st gen antipsychotics

risk of neuroleptic malignatn syndrome, higher EPS symptoms and tardive dyskinesia

Severe side effects 1st gen antipsychotics

tardive dyskinesia is irreversible

PNA 1st gen antipsychotics

monitor with AIMs scale

What is risperidone (risperdal)

2nd gen antipsychotics

What is clozapine (clozaril)

2nd gen antipsychotics

What is apiprazole (abilify)

2nd gen antipsychotics

What is olanzapine (zyprexa)

2nd gen antipsychotics

MOA 2nd gen antipsychotics

block dopamine and serotonin receptors

Common side effects 2nd gen antipsychotics

higher metabolic issues, risk of NMS

Risk with clozapine

agranulocytosis

Risk of risperidone

high prolacin

PNA 2nd gen antipsychotics

monitor metabolic changes

What is hydroxyzine (vistaril) used for?

antihistamine, PRN for anxiety

What is Mirtazipine (remeron) used for?

atypical antidepressant, can cause weight gain

What is trazodone used for?

sleep

What is vilazodone (viibryd) used for?

antidepressant

What is Vortioxetine (trintellix) used for?

antidepressant