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Which ventricle holds more blood at end‑diastole?
RV EDV > LV EDV (RV holds slightly more blood).


Causes of RV pressure overload
Pulmonary hypertension, pulmonic stenosis.


Causes of RV volume overload
Tricuspid regurgitation, pulmonic regurgitation, atrial septal defect.


How do pulmonary arterioles respond to oxygen?
They dilate in the presence of oxygen


How does pulmonary embolism cause hypotension?
Blocked pulmonary arteries → CO forced through fewer vessels → ↑PVR → RV failure → hypotension.


Effect of left‑to‑right shunt on pulmonary vasculature
Systemic pressure damages pulmonary arteries → hypertrophy → ↑PVR → impaired oxygenation.



What causes reversal to right‑to‑left shunt?
PVR > SVR → deoxygenated blood enters systemic circulation.


Signs of Eisenmenger syndrome
Clubbing, polycythemia, hemoptysis, heart failure.


Is Eisenmenger reversible?
No — irreversible pulmonary hypertension


What is Tetralogy of Fallot?
VSD + Pulmonic stenosis + Overriding aorta + RV hypertrophy. PROV


What is L‑TGA (Congenital Corrected Transposition of the Great Arteries)?
TGA=Transposition of Great Arteries=>Congenital corrected transposition where RV becomes systemic ventricle.


Natural history of systemic RV (L‑TGA)
RV fails in 30s–40s due to chronic systemic workload.


ECG finding suggesting RV infarct in inferior MI
ST elevation in II, III, aVF plus ST elevation in V1


