Cell Cycle Protein Functions

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Last updated 9:39 PM on 10/8/26
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6 Terms

1
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Cyclin

A family of proteins that act as a key regulators of the cell cycle. Levels fluctuate throughout the cell cycle, allow the cell to move from G1 into S

2
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CDK

Key regulatory enzymes in cell division that phosphorylate target proteins, levels are constant

3
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Rb

A cell cycle “brake” that prevents transcription of S-phase genes by blocking the activity of key transcription factors

4
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E2F

A proto-oncogene that transcribes S-phase genes which allows the cell to move from G1 to S

5
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CDKI

Blocks cell division by preventing CDKs from phosphorylating their targets

6
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p53

Prevents cells with damaged DNA from dividing by either halting the cell cycle for DNA repair or triggering apoptosis, tumor suppressor