FNN100 - Module 6: Thiamin (subject to update)

What are the functions of thiamin?

Produces enzyme cofactor involved in metabolism and produces neurotransmitters.

Which vitamin produces neurotransmitters?

Thiamin

Which vitamin is involved in energy metabolism?

Thiamin.

What is Thiamin Deficiency called?

Beriberi

What are the symptoms of Beriberi?

Anoxeria, weakness/fatigue, neurological symptoms, and heart complications.

What characterizes wet Beriberi?

It causes edema.

What does dry Beriberi affect?

It affects the central nervous system/nerve function.

Where is thiamin absorbed in the body?

Jejunum/ileum (small intestine).

What is the method of thiamin absorption at low concentration?

Carrier mediated absorption.

What method of thiamin absorption occurs at high concentration?

Passive diffusion.

How are water-soluble vitamins excreted from the body?

Via urine.

What is Wernicke-Korsakoff Syndrome (WKS)?

A neurodegenerative disorder caused by severe thiamin deficiency associated with alcoholism.

What are the causes of Wernicke-Korsakoff Syndrome (WKS)?

Alcoholism and malnutrition.

What are dietary sources of thiamin?

Pork, yeast, legumes, and wheat germ.

Toxicity or UL (upper limit) for Thiamin

There is no known toxicity or UL (upper limit).

What are Anti-Thiamin Factors (ATF)?

Enzymes that occur naturally in food and function to degrade thiamin.