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Isotopes
Different forms of an element with the same number of protons but different numbers of neutrons, leading to variations in atomic weight.
Hydrogen Bonds
Weak chemical bonds formed between a hydrogen atom and an electronegative atom like oxygen or nitrogen.
Nucleic Acids
Biological macromolecules like DNA and RNA made of nucleotide monomers held together by phosphodiester bonds.
Translation
The process of protein synthesis where ribosomes match mRNA codons to tRNA anticodons to build a polypeptide chain.
Mitosis
Cell division resulting in two identical daughter cells with the same chromosome number as the parent cell.
Gene Expression
The process by which information from a gene is used to synthesize a functional gene product like a protein.
Recombinant DNA
DNA molecules formed by combining DNA from different sources using techniques like restriction enzymes and DNA ligase.
Hardy-Weinberg Theorem
Mathematical model stating that allele frequencies in a population will remain constant over generations if certain conditions are met.
Transcription Factors
Proteins that regulate gene expression by binding to specific DNA sequences and controlling the transcription of genetic information.
Central Dogma
The flow of genetic information from DNA to RNA to proteins, representing the fundamental principle of molecular biology.
Protein Structure
The chemical characteristic of amino acid R-groups and their interaction with water's solvation shell, influencing protein folding into tertiary structure with levels including primary, secondary, tertiary, and quaternary structures.
Translation
Involves initiation, elongation, and termination mechanisms, focusing on ORFs, DNA mutations like point mutations (silent, missense, nonsense) and insertions/deletions causing frame shifts.
Catalysis of Translation
Ribosomes catalyze translation through the peptidyl transferase reaction adding amino acids to the polypeptide and the translocase reaction moving the ribosome along mRNA in a 5’ to 3’ direction.