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What is the singly most important stimulus for bone growth in infancy and childhood
Growth hormone
Where is the growth hormone released from
Anterior pituitary gland
What modulates the activity of growth hormone
Thyroid hormone
What plays a key role in bone development during puberty in both males and females
Estrogens
How do estrogens impact bone growth
At low levels, they stimulate the growth spurt. At higher levels, they force growth plates to close quicker
What can the hyper secretion of growth hormone result in
Excessive height (gigantism)
What can deficits of growth or thyroid hormone result in
Dwarfism
How do the relative levels of estrogens and testosterone impact bone development
They play a role in the masculinity/feminism of certain parts of the skeleton