COMLEX Bugs and Drugs Parasites

Acanthamoeba spp. Granulomatous amoebic encephalitis

Ketoconazole, rifampin, TMP-SMX

Acanthamoeba spp. Amebic keratitis

Chlorhexidine, propamidine

Babesia microti babesiosis

Clindamycin plus quinine

Balantidium coli Bloody diarrhea

Tetracycline

Cryptosporidium parvum Watery diarrhea

Nitazoxanide

Cyclospora cayetanensis Watery diarrhea

TMP-SMX

Entamoeba histolytic Bloody diarrhea

Metronidazole followed by paromomycin

Giardia lamblia Watery diarrhea (malabsorption)

Metronidazole (tinidazole)

Isospora belli Watery diarrhea

TMP-SMX

Leishmania braziliensis Mucocutaneous Leishmaniasis

Sodium stibogluconate

Visceral leishmaniasis

Liposomal amphotericin B

Microsporidia Watery diarrhea or ocular infection

albendazole or umagillin

Naegleria fowleri Primary amebic meningoencephalitis

Amphotericin B + rifampin

Trypanosoma cruzi Chagas disease

Benznidazole

Plasmodium vivax malaria

Chloroquine + primaquine

Toxoplasma gondii encephalitis

Pyrimethamine and a sulfonamide

Trichomonas vaginalis trichomoniasis

metronidazole

Trypanosoma brucei Acute (hemolymphatic)

Suamarin

Trypanosoma brucei african sleeping sickness

Melarsoprol

Plasmodium falciparum general malaria

Chloroquine

plasmodium falciparum cerebral malaria

IV quinine

Anisakis simplex Vomiting

None

Ancylostoma braziliense Cutaneous larval migrans

thiabendazole

Ancylostoma duodenale Hookworm

Albendazole

Ascaris lumbricoides Roundworm

albendazole

Brugia malayi Tropical pulmonary eosinophilia

Diethylcarbamazine

Enterobius vermicularis pinworm

Mebendazole

Loa loa Eye worm

diethylcarbamazine

Necator americanus Hookworm

Albendazole

Onchocerca volvulus African River Blindness

diethylcarbamazine

Strongyloides stercoralis Threadworm

ivermectin

Toxocara canis, T. cati Visceral larval migrans

albendazole

Trichinella spiralis Trichinosis

Albendazole (for adult worms)

Trichuris trichiura Whipworm

Mebendazole

Clonorchis sinensis Chinese liver fluke

praziquantel

Fasciola hepatica sheep liver fluke

Bithionol

Fasciolopsis buski Giant Intestinal Fluke

praziquantel

Paragonimus westermani Lung fluke

praziquantel

Schistosoma haematobium hematuria

praziquantel

Schistosoma mansoni Bloody diarrhea

praziquantel

Diphyllobothrium latum Fish Tapeworm

niclosamide

Echinococcus spp. Hydatid cyst disease

Albendazole or mebendazole

Taenia saginata Beef Tapeworm

praziquantel

Taenia solium Pork Tapeworm

praziquantel

Taenia solium cysticercosis

praziquantel