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Sensory function (1. In)
Detecting internal stimuli; increase in blood activity; 5 senses & inside body
Integrative function (2. Process)
Analyzing (& storing some) sensory info; make decisions for responses; Brain 99%, reflex(1%)
Motor function (3. Do gland or muscle)
Respond to integration decisions; motors/ efficient neurons carry info from brain to spinal cord/body parts
Structures/functions of the nervous system
Influence all functions in the human body
Senses internal & external conditions
Allow communion, coordination, & interaction of tissues, systems, and between the body and external environment
Is divided into 2 main divisions (Central NS, Peripheral NS)
Some things hypothalamus is responsible for
Maintaining homeostasis by regulating blood pressure, appetite control/food intake, heart rate, stroke volume, sleep-wake cycles, respiration, body temp, digestion, thirst, fluid balance, etc
Sympathetic NS
Fight or Flight response during sport or exercise. (Increase heart rate, metabolic rate, etc)
Parasympathetic NS
Regulate body’s involuntary function. Maintains homeostasis by promoting rest, relaxation, & conservation of energy. (Decrease heart rate)
Atrioventricular (AV) node
Conducts electrical pulse from the atria to the ventricles.
Extrinsic factors for heart control
Parasympathetic (lower heart rate)
Sympathetic (increase heart rate)
Endocrine (hormones) system (adrenaline)
How a stimulus brings a motor response
A sensory stimulus is received
Info travels along sensory nerves to CNS
CNS selects appropriate response
CNS sends message along motor nerves to skeletal muscles
Motor response occurs
Proprioceptors
Specialized cells located in muscles, tendons, joints, etc; Provide info about body position in space, muscle length, movement of joints. (Helps maintain balance)
Chemoreceptors
Detective chemicals in mouth, nose, and body fluids. Monitor O2, CO2, H+ in the blood. Alerts brain when there is disturbance
Baroreceptors
Pressure sensitive NC. Detect higher or lower blood pressure
Endocrine system
Regulates the body & controls the responses to physiological challenges. Release hormones from tissue/glands
Hormones
Chemicals that regulate the activities of other cells around the body. Can only interact with specific receptors for specific responses
Steroid (Hormone)
Fat soluble & pass through cell membranes to interact with receptors and elicit a response (Testosterone, Oestrogen, Progesterone)
Non-Steroid (Hormone)
Not fat soluble. Must interact with receptors on cell surface to trigger messenger chemicals inside the cell to elicit a response (Epinephrine, glycogen)
Prostaglandins
Non-steroid hormone produced in cell membrane close to site of action.
When are hormones released
When a direct stimuli is reacted
Neural (Hormone regulation)
Signals from the nervous system (Ex: Exercising = sympathetic NS increase epinephrine = increase cardiovascular)
Humoral (hormone regulation)
Relay info by responding to changes in chem of the blood (Ex: High blood glucose = increase insulin, Low blood glucose = increase glycogen)
Hormonal (hormone regulation)
Respond to changes in other hormonal levels (Ex: Empty stomach = increase appetite)
Why is pituitary gland = master gland
Is the most important endocrine and involved in maintaining homeostasis
Oestrogen (Joint Stiffness)
When oestrogen levels decrease = bone density loss = joint stiffness. Can influence production of synovial fluid. Helps reduce inflammation in joints
Oestrogen (Glycogen sparing)
Influence metabolism, muscular fitness, and body composition. Females rely on fat as source of fuel and spare more glucose
Progesterone (Thermoregulation)
Process by which body keeps a relatively constant temp over a wide range of environments and activity levels
Progesterone (Sleep Quality)
Calming & sedative effect = relaxation & drowsiness. (Promote sleep)
Homeostasis
The body’s ability to maintain constant internal environment
What does hypothalamus regulate
Blood pressure, heart rate, respiration, digestion, body temperature, thirst and fluid balance, strength of heart contractions, appetite, sleep cycle.
How does NS and endocrine work to together
NS regulates homeostasis by sending nerve endings to organs (quick). Endocrine has glands secreting hormones into blood (slow)
Feedback Mechanism
Stimulus → Sensors (receptors) → Control Center (Brain) → Effectors
Normal blood pH
7.35-7.45
CO2 is produced by
Cellular metabolism
Increase in CO2 =
Increase hydrogen ion = more acidic blood
To counter low blood pH
Respiratory control center increases rate & depth of breathing = restoring blood pH (negative feedback mechanism)
Intrinsic
Things in the heart that control how the heart beats
Sinoatrial (SA) node
Pacemaker; generates electrical impulses that cause heart contractions/pump blood. (Influenced by level of O2/CO2 & Hormones)
Extrinsic
Things outside the heart that affect heart contractions (Auto NS = Sympathetic & Parasympathetic)
Sympathetic NS on heart
Releases hormones that increase heart contractions = increase heart rate and cardiac output
Parasympathetic NS on heart
Release hormones that slow down SA node = decrease force of contraction, heart rate)
Response to too high blood sugar
Release insulin
When blood sugar gets too low
Release glucagon = promotes glycogenolysis
Insulin Sensitivity
Body needs less insulin to transport glucose cells. Exercise = uptake of glucose sensitivity by muscle cells
Insulin resistance
Pancreas produces more insulin to regulate blood sugar. Due to inactivity and high processed food.
Normal body temperature
37 +- 1 C
Where does all energy originate from
The sun (light energy)
ATP
Energy in food molecules bonds being released for muscle contraction
Muscle contraction is about…
20% efficient, 80% released as heat
Tc
Core body temperature
Shell temperature
The temp near the body surface
Metabolic rate and body heat
Increase metabolic rate = increase body heat
Ways to increase body heat/metabolic rate
Exercise, hormones, nervous system, body temp, ingestion of food, age, sex differences
4 ways heat can be transferred away from the body
Conduction, Convection, Radiation, Evaporation
Conduction
Heat generated internally can be conducted through body to clothes or air. Direct contact.
Convection
Moving heat from one place to another through the motion of air. (If cooler air = increase heat loss)
Radiation
Transfer of heat waves from one object and absorbed by another. (Body absorbs radiation heat when environment temp > skin temp)
Evaporation
Conversion of sweat to water vapor
What heat transfer method is most effective
Evaporation
Non-shivering thermogenesis
Sympathetic NS simulates increased metabolism = increase heat production
Shivering
Involuntary contractions of skeletal muscles to increase rate of heat production
Where are most sweat glands found
The back and chest
Sweating efficiency
Sometimes it isn’t evaporated and the amount of sweat produced can decrease in more humid areas
Sex differences in thermoregulation
Females: larger surface area to mass ratio = more heat produced
Males: higher sweat rate
Peripheral/Systemic Circulation
Blood pumped between heart and muscles
Pulmonary Circulation
Blood pumped between heart and lungs
Why does our respiratory and cardiovascular systems work together?
Maintaining homeostasis
Where will substance flow from
High pressure to low pressure
Mechanism of breathing (Inhale)
Diaphragm contracts downward = increase volume = decrease pressure = air rushes in
Mechanism of breathing (exhale)
Diaphragm contracts upward = decrease volume = increase pressure = push air out
Exercise effect on lungs
More energy needed = more O2 demand = increase blood acidity = increase lung volume during inhalation + faster lung compression
How does the structure of lungs facilitate gas exchange
Large Surface Area
Thin membranes
Surrounded by lots of blood vessels
Tidal Volume (Vt)
The amount of air inhaled and exhaled in a normal breath
Inspiratory reserve volume
The extra air that can be inhaled above the tidal volume (max inhale)
Expiratory reserve volume
The extra air that can be exhaled above the tidal volume (max exhale)
Vital capacity
The amount of air moved during a max inhale and max exhale
Residual Volume
The amount of air left in the lungs that cannot be exhaled. It isn’t static and is still constantly getting exchanged
Lung volumes and growth
Lung volume grows by 28 times to a max of 5.5L age 25.
Minute ventilation (Ve)
The volume of air being exhaled per minute
Minute ventilation equation
Ve(1min^-1) =60/hrs Vt(1breath^-1) X Bf(breaths min^-1)
Breathing frequency
Bf
Ve during exercise
Ve increase by Vt & Bf to maintain resting gas pressure
4 components of blood
Plasma
Platelets
Leucocytes (White Blood Cell)
Erythrocytes (Red Blood Cell)
Plasma
Fluid. Mixture of water & dissolved substances (55% blood volume)
Platelets
Assist in repair after injury. Major role in blood clotting. Fragments of cells (<1% blood volume)
Leucocytes (White Blood Cells)
Involved in immune protection against infection (<1% blood volume)
Erythrocytes (Red Blood Cell)
Carry oxygen from lungs to tissue and CO2 to lungs. % of blood cells = haenatocrit. (40-45% of blood volume)
Hemoglobin
Iron rich pigment in blood. Easily binds with O2 in high partial pressure. Diffuses O2 to organs in low pp.
Erythropoietin
Increases RBC creation and there for O2 capacity. Increase hemoglobin
Legal ways to increase erythropoietin
Training at high altitudes or wearing gas masks
Illegal ways to increase erythropoietin
Blood doping and injections
3 main blood vessels
Arteries
Capillaries
Veins
Arteries
Large diameter. Thick muscle walls. Transport O2 rich blood away from heart to tissues
Capillaries
Supplied by arterioles. Narrow & thin walls. Sites of exchange between blood and tissue
Veins
Deliver mostly deoxygenated blood to the heart. Less muscular and fibrous than arteries. Flexible & contain valves = no back flow
Cardiac Cycle
Heart is a 4-chambered double pump system. Left & right sides of heart in parallel simultaneously. Atrium receives blood from vein. Ventricles push blood to arteries
Atrium
Receive blood from a vein
Ventricles
Push blood out of the heart into an artery
Hepatic
Drain the liver
Mesenteric
Carry nutrient blood from intestines