USP DESCRIPTIVE TERMS FOR SOLUBILITY

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Last updated 8:02 AM on 9/17/26
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14 Terms

1
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Very Soluble (VS)

Parts of Solvent Required for One part of Solute:

2
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Very Soluble (VS)

Solubility Range (mg/mL or g/L):

> 1000

3
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Freely Soluble (FS)

Parts of Solvent Required for One part of Solute:

1 - 10

4
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Freely Soluble (FS)

Solubility Range (mg/mL or g/L):

100 - 1,000

5
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SOLUBLE (S)

Parts of Solvent Required for One part of Solute:

10 - 30

6
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SOLUBLE (S)

Solubility Range (mg/mL or g/L):

33 - 100

7
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SPARINGLY SOLUBLE (SPS)

Parts of Solvent Required for One part of Solute:

30 - 100

8
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SPARINGLY SOLUBLE (SPS)

Solubility Range (mg/mL or g/L):

10 - 33

9
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SLIGHTLY SOLUBLE (SS)

Parts of Solvent Required for One part of Solute:

100 - 1,000

10
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SLIGHTLY SOLUBLE (SS)

Solubility Range (mg/mL or g/L):

1 - 10

11
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VERY SLIGHTLY SOLUBLE (VSS)

Parts of Solvent Required for One part of Solute:

1,000 - 10,000

12
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VERY SLIGHTLY SOLUBLE (VSS)

Solubility Range (mg/mL or g/L):

0.1 - 1

13
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PRACTICALLY INSOLUBLE (PI)

Parts of Solvent Required for One part of Solute:

> 10,000

14
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PRACTICALLY INSOLUBLE (PI)

Solubility Range (mg/mL or g/L):

< 0.1