Pharmacology Exam 4 Drugs

Special coronary vasodilators

• Adenosine

• Regadenoson

Adjunctive Drug: Antianginal

• Ivabradine

• Ranolazine

Dihydropyridines

Amlodipine, felodipine, isradipine, nicardipine, nifedipine, clevidipine

Non-dihydropyridines

• Verapamil

• Diltiazem

Class 1A

• Quinidine

• Procainamide

• Disopyramide

Class 1B

• Lidocaine

• Mexiletine

Class 1C

• Propafenone

• Flecainide

Class II: BBs

• Propanolol

• Metoprolol

• Esmolol

• Sotalol

Class III: K+ blockers

• Amiodarone

• Dronedarone

• Sotalol

• Dofetilide

• Ibutilide

Class IV: Ca2+ Blockers

• Verapamil

• Diltiazem

A1 Agonist

Adenosine

ATPase Inhibitors

Digoxin

ACEi & ARBs

• Enalapril

• Losartan

ARNIs

Sacubitril/Valsartan

SGLT2i

• Dapagliflozin

• Empagliflozin

• Canagliflozin

• Sotagliflozin

MRA

• Spironolactone

• Eplerenone

• Finerenone

BilDil

Hydralazine/Isosorbide

CA Inhibitors

Acetazolamide

Osmotic Diuretics

Mannitol

Loop Diuretics

• Furosemide

• Torsemide

• Bumetanide

• Ethacrynic Acid

Thiazides

• Hydrochlorothiazide

• Chlorthalidone

• Indapamide

• Metolazone

K Sparing

• Spironolactone

• Triamterene

• Amiloride

ADH Antagonist

• Tolvaptan

• Conivaptan

HMG-Co Reductase Inhibitors (statins)

• Atorvastatin

• Lovastatin

• Pravastatin

• Rosuvastatin

• Simvastatin

ACLY Inhibitor

Benpedoic Acid (Nexletol)

NPC1L1 Inhibitor

Ezetimibe

PCSK9 Inhibitor

• Alirocumab

• Evolocumab

• Inclisinam (siRNA)

• Enlicitide (Oral)

Bile Acid Sequestrants

• Cholestyramine

• Colestipol

• Colesevelam

MTP Inhibitor

Lomitapide

ApoB-100 Inhibitor

Mipomersen

ANGPTL3 Inhibitor

Evinacumab

DGAT Inhibition

Fish Oil (Omega-3)

Activation of PPAR-alpha receptors

• Fenofibrate

• Gemfibrozil

• Clofibrate

Direct Renin Inhibitor

Aliskiren

Dopamine D1 Agonist

Fenoldopam