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Which kind of tests are used when the organism is difficult or DANGEROUS to culture?
Febrile Agglutinins
What kind of organisms are identified in the Febrile Agglutinins tests?
FEVER causing organisms that are difficult to work with
What exactly do Febrile Agglutinins detect for?
AGGLUTININS
These detect for ANTIBODIES for the organism
Which 2 factors cause Agglutination?
Patient antibody + bacterial antigens
forming a lattice
What is described as the highest dilution before you see agglutination?
Titer
What is the 1st step of Febrile agglutinins?
Patient is exposed to febrile illness and CREATES ANTIBODY
What is the 2nd step of Febrile agglutinins?
MIX patient serum with KILLED BACTERIAL ANTIGEN
What is the 3rd step of Febrile agglutinins?
LOOK FOR CLUMPING
What is the 4th step of Febrile Agglutinins?
SERIAL DILUTIONS