Thesis meet-up 2 MAIN

What is mTOR?

mTOR is a protein that senses nutrients and regulates cell growth and metabolism

What are mTORC1 and mTORC2?

Two protein complexes that regulate cell growth, metabolism, and other cellular functions

What activates mTORC1?

Amino acids, growth factors, and sufficient energy

What is the main function of mTORC1?

It promotes protein synthesis and cell growth when nutrients are available

What is metabolism?

The processes by which an organism obtains, uses, and stores energy

What is adipose tissue?

Fat tissue that stores energy and produces hormones that regulate metabolism

What are the three main types of adipose tissue?

White adipose tissue, brown adipose tissue, and beige adipose tissue

What is the difference between white and brown fat?

White fat mainly stores energy, while brown fat burns energy to produce heat

What is UCP1?

A protein in brown fat mitochondria that helps produce heat

What does innervation mean?

The supply of nerves to a tissue or organ

What is sympathetic innervation of adipose tissue?

Nerve input that can stimulate fat breakdown and heat production

What is norepinephrine?

A neurotransmitter released by sympathetic nerves that can stimulate metabolic activity in adipose tissue

What is lipolysis?

The breakdown of stored fat into fatty acids and glycerol

How are the nervous system and metabolism connected?

Nerves can regulate how the body stores fat, mobilizes energy, and produces heat

Why study adipose tissue innervation in mice?

To understand how nerves regulate fat tissue and how this affects whole body energy balanc