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nervous system
the body's speedy, electrochemical communication network, consisting of all the nerve cells of the peripheral and central nervous systems
central nervous system (CNS)
includes the brain, spinal cord, and interneurons; makes decisions for the body
nerves
bundled axons that form neural "cables" connecting the central nervous system with muscles, glands, and sense organs
reflex
a simple, automatic response to a sensory stimulus, such as the knee-jerk response; bypasses the brain
autonomic nervous system
the part of the peripheral nervous system that controls self-regulated actions of the glands and internal organs (such as the heart); consists of the sympathetic and parasympathetic system
sympathetic nervous system
arouses the body, mobilizing its energy in stressful situations; regulates "fight, flight, and freeze" response
peripheral nervous system (PNS)
the sensory and motor neurons that connect the central nervous system (CNS) to the rest of the body
somatic nervous system
controls voluntary skeletal muscles
parasympathetic nervous system
calms the body, conserving its energy; "rest and digest" response
neurons
a nerve cell; the basic building block of the nervous system
cell body
largest part of a typical neuron; contains the nucleus and much of the cytoplasm
dendrites
branchlike parts of a neuron that are specialized to receive information
axon
the extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons or to muscles or glands
myelin
a fatty substance that helps insulate neurons and speeds the transmission of nerve impulses
synapse
the gap between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron; also known as synaptic gap or synaptic cleft
glial cells
brain's "support staff;" protect, nourish, and clean up after neurons; maintains environment for neurons to function properly
reflex arc
the nerve pathway involved in a reflex action including at its simplest a sensory nerve and a motor nerve with a synapse between
sensory neurons
found in the PNS; afferent neurons that approach & carry info to the CNS
motor neurons
found in PNS; efferent neurons that exit the CNS & carry info to muscles & glands
interneurons
neurons within the brain and spinal cord that communicate internally and intervene between the sensory inputs and motor outputs
action potential
a neural impulse; a brief electrical charge that travels down an axon; also called a depolarized state
All-or-Nothing Principle
the principle that once the electrical impulse reaches a certain level of intensity (its threshold), it fires and moves all the way down the axon without losing any intensity
depolarization
the process during the action potential when sodium is rushing into the cell causing the interior to become more positive
reuptake
picking up leftover transmitters by the presynaptic neurons
multiple sclerosis
myelin sheath destruction; disruptions in nerve impulse conduction (signals slowed down/blocked)
neurotransmitters
chemical messengers released into the synapse
excitatory neurotransmitters
encourage neurons to fire
dopamine
both excitatory and inhibitory; AFLAME (regulates attention, focus, learning, addictions, muscle movements, excitement); too little >> ADHD, Parkinson's disease & too much >> schizophrenic hallucinations
norepinephrine
excitatory; regulates energy & fight or flight response; too little >> lack of energy (depression) & too much >> anxiety, disturbed sleep; antidepressant: SRNIs >> norepinephrine increase
GABA
inhibitory; the most common inhibitory neurotransmitter in the brain; acts in opposition to glutamate; "Get a Break Already;" calms nervous system; too little >> insomnia, anxiety, epileptic seizures, Autism Spectrum Disorder (ASD), depression, impaired cognitive functioning, schizophrenia & too much >> hypersomnia/narcolepsy
Substance P
excitatory; regulates the perception of pain
refractory period
after firing, the neuron needs time to reset before firing again
resting potential
the state of a neuron when it's ready to fire but hasn't yet
threshold
-55mV; must be surpassed for electrical impulse to be triggered and sent down to axon
Myasthenia Gravis
autoimmune disorder where ACh receptors are attacked leading to muscle weakness
inhibitory neurotransmitters
block neural messages & decrease stimulation
serotonin
inhibitory; MASH (mood, sleep, attitude, hunger); too little >> depression, anxiety, OCD, insomnia & too much >> serotonin syndrome (mild to extreme); antidepressants: SSRIs >> serotonin increase
glutamate
excitatory; the most common excitatory neurotransmitter in the brain; CLAM (regulates communication, learning, acts in opposition to GABA, regulates memory); too little >> poor neural communication, fatigue, poor memory and concentration & too much >> migraines, seizures
endorphins
inhibitory; offers pain relief & positive emotions; natural painkillers released with intensive exercise
Acetylcholine (ACh)
both excitatory and inhibitory; M & M (regulates initiation of muscle memory and memory formation, consolidation, and retrieval); too little >> Alzheimer's disease, lack of muscle contraction, paralysis & too much >> muscle spasms
electrical
within nerve cells
chemical
between nerve cells