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What is the functional unit of the kidney?
Nephron
What is the outer region of the kidney?
Renal cortex
What is the inner region of the kidney?
Renal medulla
What is the kidney hilus?
The area where blood vessels, nerves, and the ureter enter or leave
What do the ureters do?
Carry urine from the kidneys to the bladder
What does the urethra do?
Carries urine from the bladder out of the body
What is the main function of the glomerulus?
Filters water and small solutes from the blood
What surrounds the glomerulus?
Bowman's capsule
What does the afferent arteriole do?
Carries blood into the glomerulus
What does the efferent arteriole do?
Carries blood away from the glomerulus
What is the main function of the proximal convoluted tubule?
Reabsorbs most filtered water, nutrients, and other useful substances
What is the function of the Loop of Henle?
Creates a concentration gradient that helps the kidneys conserve water
What does the distal convoluted tubule do?
Adjusts electrolyte levels and the final composition of urine
What does the collecting duct do?
Collects filtrate and helps regulate water reabsorption
Where are the renal pyramids located?
Renal medulla
What does renin help regulate?
Blood pressure
What does erythropoietin (EPO) stimulate?
Red blood cell production
What is osmosis?
Movement of water across a selectively permeable membrane
Which ion is especially important in regulating extracellular fluid balance?
Sodium
What is glomerular filtration?
Movement of water and small solutes from blood into the nephron
What is tubular reabsorption?
Movement of useful substances from the nephron back into the blood
What is tubular secretion?
Movement of selected substances from blood into the nephron tubule
What are the main functions of the urinary system?
Remove wastes and regulate water, electrolytes, and acid-base balance
What usually happens to urine output when the body is dehydrated?
Urine output decreases as the kidneys conserve water
Why does urine output decrease when the body needs to conserve water?
More water is reabsorbed into the blood
How does the circulatory system help the urinary system?
Carries blood and metabolic wastes to the kidneys
What does retroperitoneal mean?
Located behind the peritoneum
What helps protect and hold the kidneys in place?
Renal capsule, surrounding fat, and renal fascia
What is uremia?
Accumulation of urea and other wastes in the blood
What is anuria?
Little or no urine production
What is urinary incontinence?
Involuntary loss of urine
Why are women more susceptible to urinary tract infections?
The urethra is shorter and its opening is closer to the anus
What is the path of urine after the collecting ducts?
Renal pelvis → ureter → bladder → urethra
Why are blood cells normally absent from kidney filtrate?
They are generally too large to pass through the filtration barrier
What is urea?
A nitrogen-containing waste product removed from the blood by the kidneys
What is the main function of the urinary bladder?
Temporarily stores urine
What receives urine before it enters the ureter?
Renal pelvis
What is an electrolyte?
A substance that forms electrically charged ions in solution
Why is electrolyte balance important?
It helps maintain fluid balance and normal cell function
What is the difference between a ureter and a urethra?
Ureters carry urine to the bladder; the urethra carries urine outside the body
What is active transport?
Movement of substances against their concentration gradient using energy
What is the primary function of the respiratory system?
Exchange oxygen and carbon dioxide
What happens to the diaphragm during inhalation?
It contracts, flattens, and moves downward
What happens to thoracic cavity volume during inhalation?
It increases
What happens to lung pressure during inhalation?
It falls below atmospheric pressure, allowing air to enter
What happens during normal exhalation?
Thoracic volume decreases, lung pressure rises, and air moves out
Which intercostal muscles assist inhalation?
External intercostal muscles
What is the windpipe called?
Trachea
Which structure is shared by the respiratory and digestive systems?
Pharynx
What is the glottis?
The opening of the larynx into the airway
What does the epiglottis do?
Helps keep food and liquid out of the airway during swallowing
What can happen if food enters the trachea?
Aspiration, which can cause choking or lung complications
What are the two main branches of the trachea?
Right and left primary bronchi
What is the pathway of air into the lungs?
Trachea → bronchi → bronchioles → alveoli
Where does most gas exchange occur?
Alveoli
What are alveoli?
Tiny air sacs surrounded by pulmonary capillaries
Which direction does oxygen diffuse at the alveoli?
From alveolar air into the blood
Which direction does carbon dioxide diffuse at the alveoli?
From blood into alveolar air to be exhaled
What is external respiration?
Gas exchange between alveoli and pulmonary blood
What is internal respiration?
Gas exchange between blood and body tissues
What is pulmonary ventilation?
Movement of air into and out of the lungs
What is tidal volume?
Amount of air inhaled or exhaled during a normal breath
What is inspiratory reserve volume?
Extra air that can be inhaled after a normal inhalation
What is expiratory reserve volume?
Extra air that can be forcibly exhaled after a normal exhalation
What is residual volume?
Air remaining in the lungs after maximal exhalation
What is dead space air?
Air in conducting passages that does not directly participate in gas exchange
Which is largest in diameter: trachea, bronchiole, alveolar duct, or alveolus?
Trachea
What do nasal conchae help accomplish?
Warm, humidify, and filter inhaled air by creating turbulence
What is the function of respiratory mucus?
Traps dust, particles, and pathogens
What do respiratory cilia do?
Move mucus and trapped particles toward the throat
What does surfactant do?
Reduces alveolar surface tension and helps prevent alveolar collapse
Why is the large surface area of alveoli important?
It allows efficient gas exchange
What do pulmonary arteries carry?
Oxygen-poor blood from the heart to the lungs
What do pulmonary veins carry?
Oxygen-rich blood from the lungs toward the heart
What is a major function of the larynx?
Conducts air and houses the vocal cords
What keeps the trachea from collapsing?
C-shaped rings of cartilage
Why are the tracheal cartilage rings important?
They help keep the airway open
What are bronchioles?
Small branching airways within the lungs
What are lung lobules?
Small subdivisions of lung tissue supplied by smaller airways
What happens to blood carbon dioxide during breath-holding?
It generally increases
What happens to blood pH as carbon dioxide increases?
It generally decreases, making the blood more acidic
How can increased carbon dioxide lower blood pH?
Carbon dioxide forms carbonic acid, which releases hydrogen ions
What usually happens to blood carbon dioxide during hyperventilation?
It decreases
How does hyperventilation usually affect blood pH?
It raises pH, potentially causing respiratory alkalosis
What is emphysema?
Damage to alveolar walls that reduces gas-exchange surface area
What can contribute to emphysema and lung damage?
Smoking, secondhand smoke, and inhaled irritants
What is chronic bronchitis?
Chronic airway inflammation often associated with excess mucus production
What happens during an asthma attack?
Airways become inflamed and narrowed, making breathing difficult
What type of cells commonly give rise to lung cancers?
Epithelial cells lining respiratory passages or other lung tissues
How does smoking harm the respiratory system?
Damages airway tissues and cilia and increases chronic lung disease and cancer risk
What separates the thoracic and abdominal cavities?
Diaphragm
What happens to the diaphragm during quiet exhalation?
It relaxes and moves upward
What moves oxygen from alveoli into pulmonary blood?
Diffusion down a partial-pressure gradient
What is the difference between ventilation and respiration?
Ventilation moves air; respiration refers to gas exchange
What happens to air pressure when thoracic volume increases?
Pressure decreases
What happens to air pressure when thoracic volume decreases?
Pressure increases
What is the main purpose of pulmonary circulation?
Moves blood between the heart and lungs for gas exchange
Why does oxygen move from alveoli into the blood?
Alveolar oxygen partial pressure is higher than in incoming pulmonary blood
Why does carbon dioxide move from blood into alveoli?
Blood carbon dioxide partial pressure is higher than in alveolar air
How does the respiratory system help regulate blood pH?
By adjusting how much carbon dioxide is exhaled