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Cluster A (ODD/Eccentric)
Paranoid, Schizoid, and Schizotypal; distant and mistrust, do not force closeness, use simple and direct communication; do not joke w/ patient
Cluster B (Dramatic/Erratic)
Borderline, Histrionic, Narcissistic, and antisocial; interactions may be emotionally intense or attention seeking, must stay professional and avoid power struggles, must be consistent among staff
Cluster C (Anxious/Fearful)
Avoidant, Dependent, Obsessive-compulsive; want connection but fear rejection, humiliation and low self esteem; strong need to be cared for and perfectionism with inflexible standards
Paranoid
distrust and suspicion, jealous and controlling factors, may project feelings; nursing must be neutral and direct
Schizoid
Detachment and limited desire for close relationships, nursing must not force socialization
Schizotypal
social deficits, odd beliefs and communication and perceptual disturbances; nursing needs to assess carefully
Histrionic
dramatic and attention seeking, may be provocative and seductive; nursing must stay professional and use concrete language
Narcissistic
entitlement and exaggerated self importance, needs admiration and lack empathy; nursing must be neutral and avoid power struggle
Borderline Personality Disorder
Severe impairment may involve lability, impulsivity, and unstable relationships with disturbed identity; splitting= difficulty holding positive and negative aspects of another person together
Borderline Personality Disorder Modalities
psychotropics used for symptom relief; psychosocial use of CBT and DBT
Antisocial Personality Disorder
must be 18 y/o for diagnosis; antagonism, disinhibition, profound lack of empathy and absent remorse or guilt, high risk behaviors with substance misuse and impulsivity
Antisocial Personality Disorder Treatment
no meds treat, but some may be used for aggression; main treatment is psychological therapies; focusing on observable behaviors and impulse control
Avoidant
friendly, accepting and reassuring; validate fears and gradually build social skills
Dependent
address current stressors and set limits without punishment; watch for countertransference
OCPD
guard against power struggles and prepare for unexpected changes, provide structure and allow reasonable time for habitual behaviors
Assessment across Personality disorders
assess suicidal and homicidal ideations, consider medical/substance issues, ask about recent loss and interpret ethnic, cultural and social context
Major Depressive Disorder
>5 symptoms during the same 2 week period, at least one is depressed mood or loss of pleasure, appetite or weight changes, sleep issues, fatigue, guilt, impaired cog. or thoughts of death, not history of mania or hypomania
Persistent Depressive Disorder
depressed mood most of the day, more days than not, >2 years in adults and >1 year in adolescents
Disruptive mood dysregulation disorder
ages 6-18, severe persistent irritability with recurrent outbursts
Premenstrual Dysphoric Disorder
cyclical mood/anxiety symptoms in the final premenstrual week that improves with onset of menses
Depression prevalence and co-morbidity
leading cause of disability in the US and worldwide, frequently occurs with other psychiatric disorders
Older adults with depression
disproportionate number of depressed older Americans die by suicide, 4 M’s include mentation, matters, mobility, and medication
Biochemical factors for depression
serotonin affects sleep, appetite and libido; Norepinephrine affects energy, concentration, libido and anhedonia
Diathesis stress model of depression
factors include environmental, interpersonal, life events, biological vulnerability and predisposition, and psychological stressors
Beck’s Cognition Triad
negative self deprecating view of self, pessimistic view of the world, believing negative
Nursing Assessment for Depression
becks depression inventory, Hamilton depression scale, geriatric depression scale, patient health questionnaire; along with sleep, movement, mood and affect, communication and support systems
First line psychotherapy interventions for depression
CBT, IPT, PST, CBT-I, group therapy and mindfulness cognitive therapy
Pharmacological Treatment for Depression
SSRI=#1, SNRI, antidepressants and MAOI’s=#2
Serotonin Syndrome
SHIVERS- shivering, hyperreflexia, increased temp, encephalopathy, restlessness, and sweating
Electroconvulsive Therapy (ECT)
used in suicidal pts, extremely agitated, severely manic or refusing food and fluids, no treatment works
Alternative Treatments for Depression
VNS and TMS, light therapy, st. johns wort, peer support and physical activity
Risk factors for suicide
a crisis, mental health/SUD, previous attempt, hopelessness, chronic illness, recent loss, access to lethal means and cultural/social context
Medical Aid in dying
legally and clinically distinct from suicide, must assess suffering, psychiatric symptoms, decision making, and safety in clinical context
Theories on suicide
Freud: murderous attack on self; Menninger: revenge depression or guilt; Shneidman: unbearable psychological pain with self destructive behaviors; Hendin: depression and suicide with no medication
Neurobiological aspects of suicide
strong association between suicide and low serotonin, biological response to stress may be risk factor, overactive noradrenergic system and hypothalamic-pituitary-adrenal axis abnormalities
Cultural Considerations with suicide
stereotyping, culture, religion, geography and community context, ask what certain things mean to patients
Sudden behavior changes with suicide
sudden or unexpected improvement of mood, giving away possessions, farewell notes, making a will, neglecting hygiene and failing to sleep
Columbia Suicide Severity Rating Scale (C-SSRS)
structured assessment of SI useful in triage and highly reliable, six questions and can evaluate lifetime and last three months
Delusional Disorder
delusions, grandiose, somatic or referential with largely intact functioning; >1 month
Brief Psychotic Disorder
sudden onset of delusions, hallucinations, disorganized speech or behavior for >1 day and <1 month, return to baseline is expected
Schizophreniform Disoreder
same symptoms as schizophrenia, impairment is not apparent yet, 1- <6months
Schizoaffective Disorder
major mood episode concurrent with symptoms of schizophrenia; psychosis is also present
Risk Factors for Schizophrenia
6x genetic risk, dopamine, glutamate and serotonin imbalances; less grey and white matter in frontal lobe; childhood trauma, poverty, and SUD
Early Onset of Schizo
around 15-25 with more structural brain abnormalities, more prominent negative and disabling symptoms with poorer prognosis
Later onset Schizo
ages 25-36, more likely to be female, less brain structure changes and better long term outcomes
Prodromal Phase of Schizo
mild changes in thinking, mood, concentration, and social functioning; 1-12 months before first episode
Acute Phase of Schizo
exacerbation of positive symptoms often the point of hospitalization
Stabilization Phase of Schizo
symptoms diminish, movement towards previous level of functioning
Maintenance phase of Schizo
a new baseline is established with focus on relapse revention
Positive Symptoms: Thought and Speech of Schizo
Thought: delusions, paranoia, thought blocking, thought insertion, and magical thinking
Speech: associative looseness, clang association, neologisms, echolalia, flight of ideas and circumstantiality v tangentiality
Positive Symptoms: Perception and Behavior of Schizo
Perception: hallucinations, illusions, depersonalization, and derealization
Behavior: Echopraxia, stereotyped behavior, posturing, catatonia
Negative Symptoms of Schizo
6 A’s- Anhedonia, avolition, asociality, affective blunting, apathy, alogia
Cognitive and Affective Symptoms of Schizo
Cog: concrete thinking, impaired memory, impaired executive functioning, anosognosia
Affective: assess for depression, SI risk, signal impending release, SUD
Implementation for Acute Phase Schizo
psychiatric and medical evaluation, meds, education, *monitor for polydipsia
First generation Antipsychotics
Haldol, Chlorpromazine and Fluphenazine; dopamine antagonist, positive treatment; mx for EPS, tardive dyskinesia and anticholinergic
Second generation Antipsychotics
Clozapine, Risperidone, Olanzipine and Paliperidone; serotonin and dopamine antagonist, treats positive and negative symptoms; monitor for weight gain and metabolic syndrome
Neuroleptic Malignant Syndrome
signs= muscle rigidity, fever, high CPK, diaphroesis and unstable BP, decreased responsive
response= hold antipsychotic, cooling and hydration; Dantrolene or Bromocriptine
Anticholinergic Toxicity
signs= hot and dry, urine retention, dilated pupils and tachy, delirium
response= hold all meds, cool and cath, sedate and use physostigmine
Cognition and 6 domains
the mental process of acquiring knowledge and understanding through thought, experience and senses; affects all parts of life; 6 domains=complex attention, executive functioning, learning and memory, language, perceptual motor abilities, and social cognition
Delerium
acute, transient disturbance, caused by an underlying physiological problem that is usually reversible and a medical emergency
Delirium signs
disturbances in attention and awareness, abrupt onset with lucid period, poor recall, disorganized thinking, *Illusions
Risk factors for delirium
cognitive impairment, infection, dehydrated, sleep deprivation, immobilization, vision or hearing impairment and psychoactive meds
Type of Delirium
Hyperactive= restlessness, pacing, agitation, rapid mood swings
Hypoactive= reduced anxiety, sluggish, drowsy, dazed *least recognized
Mixed= switches between hyper and hypo active
Delirium Assessment
Physiological disturbances, baseline vitals, LOC, onset, and worsening or improving factors; care for them by reorienting them
Mild NCD
modest decline in one or more domains; affects 20% of adults over 65, independence in ADL’s preserved, not due to mental disorders
Major NCD
Significant decline in more than one domain, interferes with daily functioning and independence, progresses
Causes of Major NCD
Alzheimer’s, CVA, Lewy body dementia, frontotemporal, parkinson’s, TBI
Alzheimer’s Signs
memory loss, executive dysfunction (problem solving), aphasia, apraxia, agnosia, diminished emotional expression
Alzheimer’s Assessment
confabulation(making up stories), preservation, agraphia, hyperorality, sundowning
Risk Factors for Alzheimer’s
more common in women, genetics, CV disease, head injury or trauma, late onset; modifiable risks are exercise, adequate sleep, social engagement, healthy diet, education
Alzheimer’s diagnosis
complete neuro workup, CT and PET scans, MSE, recent symptoms, rule out reversible causes
Treatment for Alzheimer’s
Cholinesterase inhibitors, NMDA receptor antagonist, anti-amyloid monoclonal antibodies, SSRI’s and sleep aids
Addiction
a chronic relapsing brain disease, compulsive drug seeking despite harm, long lasting changes in the brain
DSM-5 Criteria for SUD
impaired control with attempts to cut down unsuccessful and cravings, social impairment with giving up on activities and failing obligations, risky use, and physical effects of tolerance and withdrawal
Risk factors for SUD
genetics account for 40-60%, prenatal exposure, adverse childhood events, inadequate parental supervision, poverty
Dual Diagnosis for SUD
two or more substance use and mental health disorders together, depression anxiety, bipolar, ptsd and schizo; must treat both at the same time
Intoxication
slurred speech, unsteady gait, drowsiness, lower VS, impaired judgment and impaired memory
Overdose
cardiovascular or respiratory depression, shock, seizures, coma and death
Withdrawal
elevated VS, n/v, tremors, sweats, hallucinations, seizures, delirium
Problem Drinking
binge- 4+ drinks (w) or 5+ drinks(m) on one occasion
Heavy- binge drinking on 5+ days a month
Complications of Alcohol Use disorder
hepatitis, cirrhosis, esophagitis and gastritis, pancreatitis, cardiomyopathy, peripheral neuropathy, leukopenia, thrombocytopenia, and h/n cancer
Wernicke-Korsakoff Syndrome
thiamine deficiency, confusion, ataxia, eye movement problems(wern), memory loss, confabulation, often permanent(kor)
Alcohol Withdrawal Timeline
6-24 hours- tremors, anxiety, sweating, nausea, increased VS
12-48 hours- hallucinations and withdrawal seizures
48-72 hours- delirium tremors, disorientation, severe autonomic instability
Nursing Priorities with Withdrawal
can be fatal, stay ahead of the withdrawal, use thiamine before glucose, patients may under report use
Treatment for Withdrawal
Antabuse- must avoid alcohol including mouth wash, cough syrup
Naltrexone- reduces cravings
Acamprosate- reduces post withdrawal distress and cravings
Opioid Overdose Triad and Respone
pinpoint pupils, respiratory distress, and coma; must support breathing first, then narcan, expect sudden withdrawal
Opioid Withdrawal Timelines
8-24 hours- anxiety, cravings, yawning, sweating and runny nose
72 hours- peak, chills, fever, body aches, diarrhea, insomnia, dilated pupil
1 week+- depression, anxiety, cravings
Medications for Opioid Use
Methadone- full agonist, daily clinic based
Suboxone- partial agonist, office based
Clonidine- ease withdrawal symptoms
Stimulant Use Disorder
cocaine, crack, meth; can cause agitation, aggression, paranoia, hallucinations and anxiety; can cause tachy and MI and Stroke
Stimulant Withdrawal symptoms
depression, fatigue, sleep and concentration problems; must watch for suicide risk
Treatment for Stimulant use
no FDA meds, contingency management and CBT; bupropion may help