#21-50 of Top 100 drugs

Mounjaro

Brand name of Tirzepatide

Antidiabetic and weight loss agent

Therapeutic class of Tirzepatide

Diabetes mellitus

FDA Indication of Tirzepatide

2.5, 7.5, 10, 12.5, or 15mg per 0.5ml single dose pens

Available strengths of Tirzepatide

MOA of Tirzepatide

GLP-1 receptor agonist; selectively binds to and activates both GIP an GLP-1 receptors thereby stimulating insulin and lowering glucose secretion

2.5mg injected SQ q weekly for 4 weeks

Typical dosing of Tirzepatide

Nausea, diarrhea, vomiting, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, hypersensitivity reactions, eructation, hair loss, gastroesophageal reflux diesease.

Side effects of Tirzepatide

Tirzepatide

Generic name for Zepbound

Antidiabetic and weightloss agent

therapeutic class of Tirzepatide

Weightloss and severe obstructive sleep apnea (OSA)

FDA indication of Zepbound

2.5, 5, 7.5, 10, 12.5, or 15mg per 0.5ml single-dose pens

Available strengths of Zepbound

MOA of Zepbound

GLP-1 receptor agonist; selectively binds to and activates both GIP an GLP-1 receptors thereby stimulating insulin and lowering glucose secretion

2.5mg injected SQ qweekly for 4 weeks

Typical dosing of Zepbound

Nausea, diarrhea, vomiting, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, hypersensitivity reactions, eructation, hair loss, gastroesophageal reflux diesease.

Some side effects of Zepbound

Proventil HFA, Proair HFA, and Ventolin HFA

Brand names for Albuterol Sulfate (inhalation)

Bronchodilator

Therapeutic class of Albuterol Sulfate

Relief of bronchospasms (asthma)

FDA indication of Albuterol Sulfate

90mcg/spray

Available strength of Albuterol Sulfate

Short-acting beta-2 adrenergic receptor agonist (SABA); stimulation of beta-2-adrenergic receptors to relax bronchial uterine, and vascular smooth tissue (bronchodilation)

MOA of Albuterol Sulfate

2 inhalations q4-6 hours

Typical dosing of Albuterol Sulfate

Nausea, vomiting, nervousness, headache, insomnia, tremor, dizziness, hypertension, tachycardia, and palpitations

Side effects of Albuterol Sulfate

Lasix

Brand name for Furosemide

Diuretic

Therapeutic class of Furosemide

Edema from congestive Heart failure (CHF), Hypertension

FDA indication of Furosemide

20,40, 80mg

Available strengths of Furosemide

Loop diuretic; Primarily inhibits reabsorption of sodium and chloride in the thick ascending loop of Henle

MOA of Furosemide

20 to 80mg per day in 1-2 doses

typical dosing of Furosemide

HEARING LOSS, WEAKNESS, MUSCLE CRAMPS, ANEMIA

dizziness, dry mouth, purpura, rash, hyperglycemia, photosensitivity, nausea, vomiting

Side effects of Furosemide

Fluid/electrolyte loss (oral solution, tablet) can lead to profound diuresis with water and electrolyte depletion

Boxed warning of Furosemide

Mobic, Viviodex, Anjeso

Brand names of Meloxicam

Nonsteroidal Anti-Inflammatory

Therapeutic class of Meloxicam

Osteoarthritis and Rheumatoid Arthritis

FDA indication of Meloxicam

5, 7.5, 10, 15mg

Available strengths of Meloxicam

NSAID; inhibits cyclooxygenase which decreases biosynthesis of prostaglandins

MOA of Meloxicam

7.5mg po qday

typical dosing of Meloxicam

Abdominal pain, diarrhea, dyspepsia, flatulence and nausea

Side effects of Meloxicam

NSAIDS may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, NSAIDs have been involved in rare cases of GI bleeding incidents

Boxed warning of Meloxicam

Coreg & Coreg CR

Brand name for Carvedilol

Antihypertensive

Therapeutic class of Carvedilol

Hypertension, Heart Failure

FDA indication of Carvedilol

3.125mg, 6.25mg, 12.5mg, 25mg

CR: 10, 20, 40, 80mg

Available strengths of Carvedilol

Beta blocker; nonselective beta-adrenergic blocking agent (reduce cardiac output and tachycardia) with alpha-1-adrenergic blocking activity

MOA of Carvedilol

12.5mg po bid

Typical dosing of Carvedilol

Dizziness, diarrhea, bradycardia and hypotension, hyperglycemia, and visual abnormalities occur in treatment of congestive heart failure

side effects of Carvedilol

Microzide

Brand name of Hydrochlorothiazide

Diuretic

Therapeutic class of Hydrochlorothiazide

Edema from Congestive Heart Failure (CHF), Hypertension

FDA indication of Hydrochlorothiazide

12.5, 25, 50mg

Available strengths of Hydrochlorothiazide

Thiazide diuretic; inhibits the reabsorption of sodium and chloride at the distal renal tubule

MOA of Hydrochlorothiazide

25 to 100mg po qday in single or divided dose

Typical dosing of Hydrochlorothiazide

Dry mouth, muscle cramps, nausea, vomiting, anemia, weakness, dizziness, orthostatic hypotension, anorexia, GI distress including diarrhea and constipation, hyperglycemia, photosenstivity, rash and transient blurred vision

Side effects of Hydrochlorothiazide

Prednisone

Generic name for Deltasone

Anti-inflammatory

Therapeutic class of Prednisone

Allergic and inflammatory disease

FDA indication of Prednisone

1,2.5,5,10,20,50mg

Available strengths of Prednisone

Corticosteroid; Adrenocorticoids bind to form steroid-receptor complex that reacts with chromatin/DNA to inhibit transcription of mRNA

MOA of Prednisone

Dosage must be individualized; 5 to 60mg po day

Typical dosing of Prednisone

Lamictal (XR, ODT, CD)

Brand name of Lamotrigine

Anticonvulsant/Bipolar Agent

Therapeutic class of Lamotrigine

Seizures

FDA indication of Lamotrigine

5,25,100,150, 200mg

XR: 100mg

Available Strengths of Lamotrigine

inhibits voltage-sensitive Na channels to suppress release of glutamate

MOA of Lamotrigine

25 to 200mg po qday

Typical dosing Lamotrigine

Flomax

Brand name of Tamsulosin Hydrochloride

BPH Agent

Therapeutic class of Tamsulosin Hydrochloride

Benign Prostatic Hyperplasia (BPH)

FDA indication of Tamsulosin Hydrochloride

0.4mg

Available strength of Tamsulosin Hydrochloride

Selectively blocks alpha-adrenergic in prostate

MOA of Tamsulosin Hydrochloride

0.4mg po day

Typical dosing of Tamsulosin Hydrochloride

Ultram (ER)

Brand name for Tramadol Hydrochloride

Analgesic

Therapeutic class of Tramadol Hydrochloride

Moderate to moderately severe pain

FDA indication of Tramadol Hydrochloride

50,100,200,300mg

Available strengths of Tramadol Hydrochloride

Binds to m-opioid receptor and inhibits reuptake of norepinephrine and serotonin

MOA of Tramadol Hydrochloride

50 to 100mg pq 4-6hrs prn for the relief of pain, not to exceed 400mg/daily

Typical Dosing of Tramadol Hydrochloride

Klonopin

Brand name for Clonazepam

Antianxiety Agent

Therapeutic class of Clonazepam

Anxiety, Antiseizure

FDA Indication of Clonazepam

0.5,1,2mg; (Wafer) 0.25mg

Available strengths of Clonazepam

Benzodiazepine; inhibits gamma-aminobutyric acid (GABA)

MOA of Clonazepam

0.5mg po TID

Typical Dosing of Clonazepam

Plavix

Brand name of Clopidogrel Bisulfate

Hematological Agent

Therapeutic class of Clopidogrel Bisulfate

Reduce risk of atherosclerotic events

FDA indication of Clopidogrel Bisulfate

75, 300 mg

Available strength of Clopidogrel Bisulfate

Converted by CYP2C19 to active metabolite to inhibit platelet aggregation by prevention ADP and receptor binding

MOA of Clopidrogel Bisulfate

75 mg po day

Typical dosing of Clopidogrel Bisulfate

Singulair

Brand name of Montelukast Sodium

Antiasthmatic/Antiallergy

Therapeutic class of Montelukast Sodium

Asthma, Seasonal Allergies

FDA indication of Montelukast Sodium

4,5, 10mg

Available strengths of Montelukast Sodium

Binds to CysLT1 receptor to inhibit LTD4 in the lungs

MOA of Montelukast Sodium

10mg po qday in the evening

Typical dosing of Montelukast Sodium

Headache, influenza, cough, abdominal pain, dyspepsia, and dizziness

Side effects of Montelukast Sodium

Serious neuropsychiatric events

Boxed warning of Montelukast Sodium

Zofran, Zuplenz

Brand names of Ondansetron Hydrochloride

Antiemetic

Therapeutic Class of Ondansetron Hydrochloride

Nausea and Vomiting

FDA indication of Ondansetron Hydrochloride

4, 8mg

Available strengths of Ondansetron Hydrochloride

Selective 5-Ht3 receptor antagonist in vagal nerve terminals and chemoreceptor trigger zone

MOA of ondansetron hydrochloride