Phosphatidylinositol Second Messenger System DAG

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Last updated 2:53 AM on 3/18/25
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5 Terms

1
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STEP 1

The ligand binds to its receptor, activating the G protein

2
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STEP 2

The alpha subunit binds and activates phospholipase C (PLC)

3
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STEP 3

PLC converts PIP2 to DAG and IP3

DAG and IP3 stimulate different parts of the cascade at the same time

4
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STEP 4 (DAG)

DAG activates protein kinase C (PKC)

5
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STEP 5 (DAG)

PKC phosphorylates proteins→ physiological response IP3