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STEP 1
The ligand binds to its receptor, activating the G protein
STEP 2
The alpha subunit binds and activates phospholipase C (PLC)
STEP 3
PLC converts PIP2 to DAG and IP3
DAG and IP3 stimulate different parts of the cascade at the same time
STEP 4 (DAG)
DAG activates protein kinase C (PKC)
STEP 5 (DAG)
PKC phosphorylates proteins→ physiological response IP3