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Where does the citric acid cycle occur within the mitochondrion?
Matrix
Which molecule combines with oxaloacetate to form citrate?
Acetyl-CoA
What is the primary purpose of the citric acid cycle?
Generate NADH and FADH₂
Which enzyme catalyzes the conversion of citrate to isocitrate?
Aconitase
Which product is formed when isocitrate is oxidized?
NADH
Decarboxylation reactions in the cycle release:
Carbon dioxide
Which molecule is regenerated at the end of the citric acid cycle?
Oxaloacetate
Which enzyme produces FADH₂?
Succinate dehydrogenase
How many NADH molecules are produced per turn of the cycle?
3
Which structure houses the electron transport chain?
Inner membrane
Cristae increase the surface area of the:
Inner membrane
Which mitochondrial compartment has a low pH during oxidative phosphorylation?
Intermembrane space
The mitochondrial matrix contains high concentrations of:
All answers are correct
Which molecule directly donates electrons to Complex I?
NADH
Which molecule donates electrons to Complex II?
FADH₂
The mitochondrial outer membrane contains large channel proteins called:
Porins
Which step of the citric acid cycle produces GTP?
Succinyl-CoA → succinate
Which molecule is formed from succinate?
Fumarate
Which enzyme catalyzes the final step of the citric acid cycle?
Malate dehydrogenase
Which mitochondrial structure contains ATP synthase?
Inner membrane
Which molecule is NOT produced in the citric acid cycle?
Acetyl-CoA
The mitochondrial genome is:
Circular
Which process occurs in the mitochondrial matrix?
Citric acid cycle
Which molecule links glycolysis to the citric acid cycle?
Acetyl-CoA
Which ion drives ATP synthesis?
Hydrogen
Which enzyme converts fumarate to malate?
Fumarase
Which molecule is produced when malate is oxidized?
NADH
Which mitochondrial structure is permeable to small molecules?
Outer membrane
Which molecule carries electrons from Complex I and II to Complex III?
Coenzyme Q
Which step of the citric acid cycle is a condensation reaction?
Citrate synthase step