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Nervous system
A complex network pf nerve fibres that functions to regulate important bodily functions
Two main types of nerves in the nervous system
Sensory nerve fibres
Motor nerve fibres
Sensory nerve fibres
Provide information to the brain and spinal cord via sensory receptors
Motor nerve fibres
Provide information/output from the brain or spinal cord to muscles and organs
Central Nervous System (CNS)
Made up of brain and spinal cord. Carries voluntary nerve impulses to skeletal muscles and skin and carries involuntary impulses to muscles and glands
Peripheral Nervous System (PNS)
All the nerves in the body including those connected to the brain and spinal cord. Consists of Somatic nervous system and Autonomic nervous system.
Somatic Nervous System
Connects the nerve fibres to voluntary muscles. Controls voluntary movements and provides sensory information back to the brain about that voluntary movement.
Autonomic Nervous System (ANS)
Connects the brain and spinal cord to internal organs, controls involuntary movement. Consists of sympathetic and parasympathetic NS's
Sympathetic Nervous System (SNS)
Plays critical role in preparing the body for stress. Controls the fight or flight system. Referred to as a catabolic system
Catabolic system
Deals with mobilizing and exerting energy
Characteristics of sympathetic ns response
HR and BP increase
Blood diverted to muscles
Respiration increases
Digestion and urination decrease
Pupils dilate
Sweat glands stimulated
Parasympathetic Nervous System (PNS)
Controls activity of organs when not in a stressful situation. Helps to restore the body back to normal state when a stressor has passed. ANS at rest. Referred to as an anabolic system.
Anabolic System
Concerned with conserving energy in our bodies and keeping things normal
The brain takes in information from the peripheral nerves, called _______ or ________ impulses, and interprets it
Sensory, afferent
Afferent/Sensory impulses
Information from the rest of the body that travels to the brain
The brain sends back _____ or ________ impulses to internal organs as well as the extremities of the body so that they can carry out necessary behaviours/movements
Motor, efferent
Efferent/motor impulses
Carry impulses from brain and spinal cord to organs that produce response such as glands and muscles. Away from CNS.
Two types of nerve impulses map onto
Sensory and motor nerves
3 main parts of brain
Hindbrain, midbrain, forebrain
Hindbrain (rhombencephalon)
Medulla, pons, cerebellum
Midbrain (mesencephalon)
Major pathway between the hindbrain and forebrain for sensory and motor impulses. Responsible for auditory an visual reflexes.
Forebrain (prosencephalon)
Composed of the diencephalon and telencephalon
Diencephalon
Thalamus and hypothalamus
Thalamus
Recognizes sensory stimulation from the environment and relays sensory impulses to the cerebral cortex - isn't involved in sense of smell
Hypothalamus
Regulates centers in the medulla, water balance, hunger and sexual appetites. Transition center between the thoughts created by the cerebral cortex and how our thoughts affect our organs.
Telencephalon/Cerebral cortex (cerebrum)
Largest portion of brain, includes left and right hemispheres. Involved in more complex functions - higher order processing, memory, and personality. 4 lobes.
Frontal lobe
Memory storage, motor cortex (ex: movement)
Parietal lobe
Registers and interprets touch, pain, pressure, temperature
Temporal lobe
Processes auditory and olfactory information
Occipital lobe
Processes visual information
Limbic system borders the
Midline of the brain
Limbic system
neural system (including the hippocampus, amygdala, cingulate gyrus, septum and hypothalamus) located below the cerebral hemispheres; associated with emotions and drives.
Parts of thalamus and hypothalamus are included in
Limbic system. Related to socially relevant behaviours.
SNS activation leads to release of two neurotransmitters
Epinephrine and norepinephrine (AKA adrenaline and noradrenaline)
Together, epinephrine and norepinephrine are called the
Catecholamines
The release of catecholamines leads to the changes associated with the
Fight or flight response
Although there are major differences between the different nervous system disorders, they do tend to share some common symptoms — things like:
Impaired cognition,
Issues with mobility,
Bladder issues,
Pain and discomfort, and
just poor overall health.
Epilepsy
Disease of the CNS where the main symptom is seizures. Idiopathic disorder that can be treated with medications and stress management techniques.
Idiopathic disorder
No specific cause has been identified, but there are lots of different things that are thought to contribute to the disorder, including head injury, certain infections, genetics, or problems with nutrition.
Cerebral Palsy
Brain damage caused by lack of O2 supply during child birth, physical trauma. Can also involve seizures, problems hearing, seeing or other senses or mental handicap.
Multiple Sclerosis
The degeneration of certain brain tissues resulting in paralysis. Autoimmune disorder in which the body attacks the myelin sheath surrounding nerves.
Parkinson's Disease
Degeneration of basil ganglia (controls smooth motor coordination). Symptoms include tremors, slow movement, and rigidity. Thought to be related to a lack of the neurotransmitter dopamine.
Huntington's Disease
Hereditary disorder involving chronic mental and physical deterioration and has a very strong genetic basis
Alzheimer's disease
Degenerative disorder of the brain affecting thinking and memory
Endocrine system
System that works closely with the nervous system to make sure our bodies are functioning properly. Responsible for slow-acting responses for a longer duration as oppose to nervous systems fast acting nature. Controlled by hypothalamus and pituitary gland.
Nervous and endocrine systems work closely together and they depend on each other to
Both stimulate and inhibit the activities they are responsible for
The endocrine system is composed of a series of glands that secrete
Hormones in the blood that make a variety of targeted changes to the body
Pituitary gland
Responsible for secreting a variety of hormones, including those that control growth, labour contractions, kidney function, and also controls the secretions of a variety of other glands
Adrenal Glands
Two small glands located on top of the kidneys. Contains adrenal cortex and adrenal medulla.
Adrenal cortex
Releases hormones called steroids - including estrogen and androgens and glucocorticoid's (Ex: cortisol)
Adrenal medulla
Secretes catecholamines (epinephrine and norepinephrine)
Both catecholamines and glucocorticoids play a big role in our response to
Stress
Diabetes
Chronic endocrine disorder in which the body is unable to manufacture or properly use insulin. Type 1 and 2.
Type 1 Diabetes
Pancreas does not produce enough insulin - usually diagnosed in childhood/adolescence. This type is thought to be an autoimmune disorder
Type 2 Diabetes
Body does not properly use insulin - more common, and usually diagnosed later in life. Typically related to lifestyle factors (e.g., diet, stress)
Hypothyroidism
Abnormally low thyroid stimulating hormone (TSH) production. Symptoms include fatigue, weight gain, depression
Hyperthyroidism
Excessive production of TSH. Symptoms include excessive sweating, weight loss, fatigue, tremors
Cardiovascular system
The transport system of the body, which is made up of the heart, blood vessels (arteries, capillaries, and veins), and blood.
Blood transports
Oxygen from lungs to tissues/CO2 from tissues to lungs;
Nutrients throughout our bodies;
Waste from cells to kidneys;
Hormones; and
Heat.
Vessels include
Arteries and veins
Arteries
Carry oxygenated blood from the heart to other organs and tissues. Include capillaries and arterioles.
Capillaries
Smaller vessels that branch off from arteries to individual cells
Arterioles
Tiny branches of the arteries
Veins
Return deoxygenated blood back to the heart
The left side of the heart takes in
Oxygenated blood from the lungs and pumps it into the aorta
Aorta
Main artery leading out of the heart.
After blood exits via aorta to the rest of the body, it comes back into
The right side of the heart, where it is pumped back into the lungs so it can be filled with oxygen again
The heart functions in a series of contractions and relaxations called the cardiac cycle, that has two phases:
Systole and diastole
Systole
Blood pumped out of the heart increasing the BP
Diastole
When the heart relaxes, BP drops, and blood is taking into the heart
Damage to the heart can occur due to
Congenital defects, infection (e.g., salmonella, meningitis), and/or damage over the lifespan (e.g., from lifestyle factors)
Atherosclerosis
Damage caused by plaque build-up (ex: Cholesterol) in the arteries. Main cause of heart disease by reducing blood flow and preventing nutrients from reaching our tissues, which can cause tissue damage.
Damage to artery walls can also cause blood clots. These manifest themselves in two main ways:
Angina pectoris and Myocardial infarction
Angina pectoris
Chest pains due to heart strain resulting from lack of O2 or inadequate removal of waste and CO2
Myocardial infarction
Blood clots blocks the flow of blood to the heart (heart attack)
Arteriosclerosis
Hardening of the arteries, leading to a decrease in elasticity and an increase in blood pressure
Aneurysm
Bulge in a weak part of an artery wall as a result of pressure; when it ruptures, can lead to death from internal bleeding and loss of BP
Phlebitis
Inflammation of a vein wall, resulting in pain, water retention, and greater likelihood of blood clots
Hypertension
Chronically high BP due to high cardiac output or blood flow resistance (peripheral resistance)
Normal BP is
120/80 - above 140/90 is hypertensive
The human body contains ____ L of blood
Five
Just over half of the blood (55%) is made up of
Blood plasma
Blood plasma
The fluid portion of blood, and the rest is made up of blood cells
Our blood cells are made by our
Bone marrow
Types of blood cells
White blood cells
Lymphocytes
Red blood cells
Platelets
White blood cells
Heal the body by absorbing and removing foreign substances. Put simply, they basically eat the foreign invaders and turn them into substances that can be disposed of easily
Lymphocytes
Produce antibodies to fight infection and disease.
Red blood cells
Contain hemoglobin and carry oxygen and CO2 throughout the body
Platelets
Contribute to blood vessel repair and blood clotting
Blood disorders can be related to either the production of
White blood cells or red blood cells
White Cell Production Disorders
Leukemia and Leukopenia
Leukemia
Bone marrow disease and form of cancer causing excessive white cells overloading the blood plasma, reducing red blood cells. The cause is unknown, but links have been discovered to chemicals and smoking
Leukopenia
White cell deficiency, leads to susceptibility to infection and disease. Often appears in conjunction with diseases like tuberculosis, pneumonia, and measles
Red Cell Production Disorders
Anemia, Aplastic anemia and Sickle cell anemia
Anemia
Too few red blood cells or low hemoglobin. Losely related to iron deficiency, because iron is important to the production of hemoglobin.
Aplastic anemia
Problems with the bone marrow in making red blood cells, which results in a lack of oxygen in the blood
Sickle cell anemia
Genetic disorder characterized by an inability to produce normal-shaped blood cells, vulnerable to rupture leaving individual susceptible to anemia.
Clotting disorders include
Hemophilia and Clots/Thromboses
Hemophilia
The body does not produce the substances required to clot the blood. Those with this disorder could bleed to death from a minor injury without medication.
Clots/Thromboses
When vessel walls are damaged due to the buildup of cholesterol, platelets adhere to the walls and build up. Could be fatal when they occur in vessels leading to the heart or brain