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what nano technology helps with cancer detection?
nanotubes, they bind to DNA with genetic changes
what nano technology helps with cancer treatment?
nanoshells, absorbs light to create extreme heat which kills nearby cells.
pros of nanotechnology?
enables targeted medicine delivery, fewer side effects
cons of nanotech?
can easily settle in lungs, causing inflammation or toxicity, high cost and research.
how do cancer vaccines work?
introduce virus’ antigen into the body, and the body kills the virus before it can do damage if it actually enters the body in the future.
phase 1:
evaluate safe dosage, side effects
phase 2:
tests effectiveness of the treatment
phase 3:
compare to the current standard of treatment
phase 4:
track long term side effects, safety in large population.
controlled clinical trial?
one group gets treatment, other does not
randomized clinical trial?
groups chosen at random
double blind clinical trial?
researcher and patient does not know who got what
open clinical trial?
both groups know treatment given
combo clinical trial?
testing medicine in combos
crossover clinical trial?
groups take a medicine, wash out period, then they switch
orphan drug trial?
used to treat rare diseases
what is the thalidommide tragedy? when did it happen?
introduced in the 1950s by a german pharmaceutical company which was branded as a drug for morning sickness and a sedative, children born of the users had severe malformations, over 10k born, half died.
how did the thalidommide tragedy affect legislation?
drug safety overhauls, drug ammendments created, making sure the drug was actually safe.