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What is the inner most layer of the nucleolus? Function?
Fibrillar Center. Site of rDNA genes called the nuclear organizing region. Transcription of rRNA occurs here
What is the middle layer of the nucleolus?
Dense Fibrillar Center. Where the splicing and processing of rRNA occurs
What is the outermost region of the nucleolus?
Granular Component. Where the assembly of pre ribosomal subunit combine with mature subunits
GAPs
GTPase Activating Protein
Stimulates GTP hydrolysis; reduces the amount of time the GTPase is in its on state
GEFs
Guanine Nucleotide Exchange Factor
Catalyzes the disassociation of GDP to exchange for GTP
GDIs
GDP dissociation inhibitors
Inhibits the release of GDP