Endocrine Meds (Thyroid)

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9 Terms

1
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Hypothyroidism

  • pale, puffy

  • skin cold and dry

  • hair is brittle

  • heart rate is lowered

  • cold intolerance

  • lethargy, fatigue, goiters


2
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Hypothyroidism Med

levothyroxine(Synthroid)

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levothyroxine(Synthroid) uses

  • synthetic preparation of T4

  • conversion to T3

  • half-life is 7 days


4
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levothyroxine(Synthroid) Adverse effects

  • Rare

  • Monitor for overdose after initial treatment

    • tachycardia, restlessness, irritability


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levothyroxine(Synthroid) education

  • takes 4-6 weeks to feel better

  • take with empty stomach 30 min before breakfast

  • measure labs

  • on it for life


6
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levothyroxine(Synthroid) interactions

  • Food and minerals causes decreased absorption of levothyroxine(Synthroid)

  • increased effects of catecholamines (dysrhythmias)

    • caffiene

  • Effects on protein binding

    • Warfarin


7
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Hyperthyroidism Med

propylthiouracil(PTU)

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propylthiouracil(PTU) uses

  • inhibits production of new thyroid hormone

  • inhibits conversion of t4 to t3


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propylthiouracil(PTU) Adverse effects

  • Agranulocytosis (low neutrophils)

  • Hypothyroidism

  • Acute liver injury