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Cellular asexual reproduction
daughter cells are identical copies of mother cell
Cellular sexual reproduction
daughter cells are not identical copies of mother cell
Sexual reproduction occurs only in____ and asexual occurs in ________
eukaryotes, all organisms
Chromatin
DNA + proteins
Human genome has how many chromosomes
46
Genome
total cellular DNA
Centromere
connection between 2 chromatids
Components of the cell cycle
Cell growth
Mitosis
Cytokinesis
Interphase
Cell growth and copying of chromosomes
M-phase
Mitosis and cytokinesis
subphases of interphase
G1 phase
S phase
G2 phase
What happens in the S phase
Chromosomes are duplicated
Where does the miotic spindle occur
metaphase
What is the miotic spindle
a structure made of microtubules that controls chromosome movement during mitosis
Kinetochores
protein complexes associated with centromeres
Cytokinesis occurs by which process IN ANIMALS
cleavage by forming a cleavage furrow
Cytokinesis occurs by which process IN PLANTS
a cell plate forms
Cell cycle control system
checkpoints determine if the cell cycle stops if somethings wrong until a go-ahead signal is received
What is the most important cell checkpoint
G1
Why is G1 the most important checkpoint??
If a cell doesnt get the go-ahead signal, it goes into G0 phase
What is the G0 phase??
a non-dividing state
Where are all the cell checkpoints??
G1 checkpoint
G2 checkpoint
M checkpoint
What is density dependent inhibition
when crowded cells stop dividing
Genes
the units of heredity
What are genes made up of
segments of DNA
Gametes
Sperm and eggs
Human asexual reproduction
offspring are genetically identical to each other and to the parent cell
Human sexual reproduction
2 parents make an offspring that have unique combinations of genes inherited from BOTH parents
Diploid
2 copies of each chromosome (2n)
Haploid
1 copy of each chromosome (n)
Somatic cells
body cells
Gametes are ___ and somatic cells are ____
haploid, diploid
F1 generation
hybrid offspring of the P generation
homologous chromosomes
two chromosomes in each pair of chromosomes
Fertilization
the union of sperm and eggs
What is the fertilized egg called?
zygote
a zygote has one set of chromosomes from ____
each parent
Why does sexual reproduction occur??
more genetic variation
Independent assortment
when homologs orient randomly and are divided randomly into daughter cells in meiosis 1
Crossing over
when homologous portions of 2 nonsister chromatids trade places and pieces of DNA are exchanged
synapsis
when homologous chromosomes pair
Genetic traits
the physical properties of an organism determined by 1 or more genes
Locus
the location of a gene on a chromosome
Alleles
versions of a gene
Homologous genes
same locus on homologous chromosomes
How are genes given to offspring
gametes
Who is Gregor Mendel??
discovered the basic principles of heredity by breeding garden peas
P generation
true breeding parents
F2 generation
when F1 individuals self or cross pollinate with F1 hybrids
what ratio of purple to white flowers in F2 gen did mendel discover
3:1
Recessive alleles are ____ proteins
nonfunctional
dominant alleles are ____ proteins
functional
Punnett square
a diagram for predicting the results of a genetic cross between individuals
law of segregation
alleles for a specific trait will sepereate from each other during gamete formation
homozygous
2 identical alleles
heterozygous
two different alleles
law of independent assortment
alleles for one trait will segregate independently of alleles for a different trait
Incomplete dominance
phenotype is somewhere between the phenotype of the parents (red x white = pink)
Codominance
Heterozygotes show combined phenotype
polygenic inhereitance
an additive effect of two or more genes on a single phenotype
epistasis
a gene at one locus that alters the phenotypic expression of a gene at a second locus
example of polygenic inheritance
skin color
example of epistasis
labrador coats
Females chromosomes are
XX
Males chromosomes are
XY
Autosomes
chromosomes that arent sex chromosomes
how many genes do X and Y chromosomes contain
X contains most while Y contains very few
For a recessive x-linked trait to be expressed, females need ___ copies of the allele while males only need ___
two copies, one copy
Color blindness is much more common in
males
if a female is heterozygous for a particular gene located on the X chromosome, she will be a _____
mosaic for that character
Example of X inactivation
tortoiseshell cats
linked genes
genes on the same chromosome that tend to be inherited together
morgans experiment of linked genes
crossing flies that differed in body color and wing size
linked genes do not assort ___
independently
recombination frequency
the farther genes are apart on a chromosome, the more chance of crossing over
equation for recombination frequency
(number of recombinant offspring)/(total number of offspring) x 100
nondisjunction
when pairs of homologs do not seperate normally during meiosis
Aneuploidy
abrnormal number of a particular chromosome
example of aneuploidy
down syndrome (trisomy 21)
Polyploidy
extra copies of entire genome - LETHAL in humans