Micro Ch. 16- Complement System (Exam 3- SG)

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Biology

Microbiology

University/Undergrad

Last updated 1:05 AM on 11/4/22
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9 Terms

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complement
a group of 30 proteins circulating in serum
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classical pathways of complement activation
initiated by the binding of antigen- antibody complexes to Clq protein.
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alternative pathways of complement activation
activated spontaneously by hydrolysis of internal C3
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membrane activated complex (MAC)
cytolysis
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What complements are MAC formed by
C5b+ C6 + C7 + C8+ C9
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Opsonization
Enhanced phagocytosis caused by C3b
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Complement C5a
attract neutrophils to wound
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most severe inherited deficiency in complement system
deficiency of C3
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C3 deficiency
leads to severe infections including those cause by meningococci and pneumococci