Pantothenic acid B5

other name

pantothenate, it is an amide (nitrogen attached to a carboxyl)

energy metabolism role

component of coenzyme A

3 major roles

energy metabolism CoA, prosthetic group acyl carrier protein ACP, protein acetylation

prosthetic group

non amino acid compound attached to a protein that gives it different properties

ACP is involved in

fatty acid synthesis

protein acetylation

donates acetate or fatty acids and alters the protein’s activity and function

succinyl CoA

important intermediate entering the Kreb’s cycle. Allso the start of fatty acid synthesis (acetyl CoA → malonyl CoA), and fatty acids can be stored as triaglycerol

beta-oxidation and CoA

fatty acids are degraded 2 carbons at a time, forming acetyl CoA, NADH, and FADH₂