Nucleotide Excision repair

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What symptom is associated with failure of this mechanism

Xeroderma Pigmentosum

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Enzymes involved

Endonucleases

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What does this repair mechanism deal with

Pyrimidine dimers

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Cause of pyrimidine dimers

Sunlight

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What is xeroderma pigmentosum

Early symptom of skin cancer

Characterised by;

Extreme photosensitivity eg sunburn

Xeroderma(dry skin) and uneven pigmentation

Neurological complications such as hearing loss

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