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Cancer
a disease in which abnormal cells proliferate in an uncontrolled fashion and spread through the body
Percentage of newly diagnosed cancer involving the skin
50%
Percentage of cancer death resulting from lung cancer
25%
Hypertrophy
increase in cell size and normal organization
Hyperplasia
increase in cell number and normal organization
Metaplasia
reversible change in the type of differentiated cell present (may include an increase in cell numbers)
Dysplasia
non-reversible change in the type of cell present, usually poorly differentiated
Neoplasia
cells are proliferating in an uncontrolled, relatively autonomous fashion
Why does cancer risk increase with age?
mutation accumulation, reduced repair,
and immune decline